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Global trade heavily depends on effective supply chain management and the strategic placement of distributors. Additionally, customer demands are becoming increasingly diverse and dynamic, with each customer expecting prompt and reliable responses from companies or distribution centers. To ensure a fast and efficient delivery process, businesses are striving to make well-informed decisions about the site selection of distribution centers or warehouses. The growth and success of online businesses, such as those on Amazon, largely hinge on the strategic site selection of their warehouses to expedite supply chain operations. This site selection process requires a comprehensive analysis of various factors. However, collecting and processing the relevant data often involves uncertainties and fuzziness. To address these challenges, the proposed research introduces a novel algorithmic approach based on distance measures within the Complex Pythagorean Fuzzy Soft Set (CPFSS) framework. The research presents the formulation of distance measures for the CPFSS, followed by the development of an algorithm. This algorithm is then applied to a real-life case study for the site selection of a warehouse for a company named HCRFT, which specializes in handicrafts. Furthermore, a detailed comparison between the proposed approach and existing models is conducted to validate and demonstrate the effectiveness of the algorithm. Finally, concluding remarks summarize the findings and implications of the study.
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http://dx.doi.org/10.1038/s41598-025-02702-8 | DOI Listing |
Langenbecks Arch Surg
September 2025
Department of Surgery HBP Unit, Simone Veil Hospital, University of Reims Champagne-Ardenne, Troyes, France.
Introduction: Pancreatic adenocarcinomas (PDAC) have a poor prognosis, with a 5-year relative Survival rate of 11.5%. Only 20% of patients are initially eligible for resection, and 50% of patients presented with metastatic disease, currently only candidates' palliative treatment.
View Article and Find Full Text PDFMol Divers
September 2025
Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, 11942, Al Kharj, Saudi Arabia.
Cyclin-dependent kinase 20 (CDK20), also known as cell cycle-related kinase (CCRK), plays a pivotal role in hepatocellular carcinoma (HCC) progression by regulating β-catenin signaling and promoting uncontrolled proliferation. Despite its emerging significance, selective small-molecule inhibitors of CDK20 remain unexplored. In this study, a known CDK20 inhibitor, ISM042-2-048, was employed as a reference to retrieve structurally similar compounds from the PubChem database using an 85% similarity threshold.
View Article and Find Full Text PDFClin Res Cardiol
September 2025
Department of Cardiology, University Heart Center, University Hospital Zurich, Center for Translational and Experimental Cardiology (CTEC), University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Background: Diabetic patients with ST-segment elevation myocardial infarction (STEMI) are at an increased risk of cardiovascular events as compared to non-diabetic patients. This analysis investigated outcomes of diabetic patients presenting with multivessel disease (MVD) and STEMI in a contemporary trial and the relevance of an immediate versus staged multivessel PCI strategy in this high-risk population.
Methods: Patients enrolled in the MULTISTARS AMI trial were stratified according to the presence/absence of diabetes.
Dalton Trans
September 2025
Department of Chemistry, University of Zululand, Private Bag X1001, KwaDlangezwa 3880, South Africa.
To overcome the potential issue of active site blockage by surfactants in colloidal synthesis, alternative synthetic approaches must be explored. In this study, we investigated both solvent-free and colloidal thermolysis routes to synthesize nickel sulfides (NiS and NiS) using sulfur-based Ni complexes, [Ni(SCO(CH))] (Ni-Xan) and [Ni(SCN(CH))] (Ni-DTC) as precursors. The solvent-free decomposition of these complexes produced ligand-free NiS and NiS in the absence or presence of triphenylphosphine (TPP), respectively.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
State Key Laboratory of Antiviral Drugs, Tianjian Laboratory of Advanced Biomedical Sciences, Pingyuan Laboratory, and College of Chemistry, Zhengzhou University, Zhengzhou 450001, China.
The C-H functionalization represents a universal and important method for constructing new C-C bonds by carrying out reactions directly on inert C-H bonds. The major challenges are to control the site-selectivity and chemoselectivity because most complex organic compounds have many similar C-H bonds or different functional groups, such as a C═C bond or O-H bond. Here, we develop a versatile copper cluster (CuNC) with high stability and dynamic catalytic sites.
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