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Purpose: To assess the real-world distance and intermediate visual outcomes, rotational stability, and adverse events (AEs) of patients implanted with a Clareon aspheric monofocal toric intraocular lens (IOL) preloaded in the AutonoMe delivery system (Alcon, USA; models CNA0T2 to CNA0T6) up to one-month postoperative.
Methods: Surgical charts from January 2021 to October 2023 were reviewed for adult patients (≥18 years) who previously received a CNA0T2 to CNA0T6 (T2 to T6) IOL during uneventful cataract surgery and were targeted for emmetropia/first minus. Overall, charts from 193 eyes of 121 patients were screened, with 161 eyes of 107 patients included in the study. Data were collected from preoperative, and postoperative records up to approximately one-month (4-5 weeks), and included monocular corrected distance visual acuity (CDVA), uncorrected and distance-corrected intermediate visual acuity (UIVA and DCIVA), residual astigmatism, and absolute IOL rotation (measured from the axis position at the end of surgery up to one-month).
Results: For the full cohort (T2 to T6 IOLs, n=161 eyes), CDVA was -0.01 ± 0.07 logMAR at one-month. Monocular UIVA was 0.22 ± 0.14 logMAR, DCIVA was 0.24 ± 0.12 logMAR, and absolute IOL rotation was 1.02 ± 1.21°. Residual astigmatism was very low (<0.01D) and consistently low across T2 to T6 IOLs. A T3 to T6 sub-analysis (n=64 eyes) found CDVA of -0.01 ± 0.07 logMAR, UIVA of 0.20 ± 0.14 logMAR, DCIVA of 0.23 ± 0.13 logMAR, and absolute rotation of 1.08 ± 1.26°. For all eyes, 1 serious ocular AE, cystoid macular edema, was identified. No serious non-ocular AEs, device deficiencies, or posterior capsular opacification were observed.
Conclusion: The Clareon aspheric monofocal toric IOL showed excellent improvement in distance visual acuity and treatment of astigmatism, with functional intermediate visual acuity and minimal rotation.
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http://dx.doi.org/10.2147/OPTH.S532933 | DOI Listing |
Patient
September 2025
PPD Evidera Patient-Centered Research, Thermo Fisher Scientific, Waltham, MA, USA.
Background: Migraine care is often suboptimal owing to undertreatment, variation in clinical outcomes and administration methods among existing treatments, and between- and within-individual heterogeneity in the clinical course of migraine. In response to these challenges, preference studies have been increasingly conducted to inform treatment decision-making and development. However, gaps remain in understanding how treatment preferences have been assessed across different migraine studies.
View Article and Find Full Text PDFEur J Orthop Surg Traumatol
September 2025
Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai, China.
Purpose: To investigate the images and treatment differences for Type IIIa atlantoaxial rotary dislocation (AARD) by comparing the imaging characteristics of patients with Type III and Type IIIa AARD.
Methods: The present study retrospectively analyzed a cohort of 35 patients who underwent posterior C1-C2 intra-articular fusion due to AARD from our hospital database. Among them, 23 patients were diagnosed with Type III AARD, while the remaining 12 patients were diagnosed with Type IIIa AARD.
Psychol Res
September 2025
Neurorehabilitation Research Center, Kio University, Nara, Japan.
The ability to detect small errors between sensory prediction in the brain and actual sensory feedback is important in rehabilitation after brain injury, where motor function needs to be restored. To date in the recent study, a delayed visual error detection task during upper limb movement was used to measure this ability for healthy participants or patients. However, this ability during walking, which is the most sought-after in brain-injured patients, was unclear.
View Article and Find Full Text PDFArch Orthop Trauma Surg
September 2025
Division of Orthopaedics and Traumatology, Cantonal Hospital Winterthur, Winterthur, Switzerland.
Background: Accurate acetabular cup orientation in total hip arthroplasty (THA) is crucial for successful outcomes. Intraoperative fluoroscopy may be used to evaluate acetabular cup placement. This study aimed to evaluate the accuracy of purely visual estimation of cup inclination and anteversion using intraoperative fluoroscopy, considering different surgeon experience levels and cup designs.
View Article and Find Full Text PDFKhirurgiia (Mosk)
September 2025
Mogilev Regional Clinical Hospital, Mogilev, Republic of Belarus.
Objective: To evaluate clinical and laboratory effectiveness of ultrasound treatment for purulent wounds.
Material And Methods: The study enrolled 46 patients with purulent wounds divided into the main group (23 patients, ultrasonic treatment) and the control group (23 patients, traditional treatment). We assessed treatment effectiveness considering visual data, quality of granulation tissue, wound defect area and marginal epithelialization, complete blood count and C-reactive protein.