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Background: Acute colonic pseudo-obstruction (ACPO) is defined as colonic obstruction without a mechanical or extrinsic inflammatory factor. Colonic decompression is advised for patients with ACPO after the failure of conservative and medical management.
Aim: To systematically review and analyze the efficacy and safety of colonoscopic decompression in ACPO.
Methods: A search was conducted in MEDLINE, EMBASE, and Scopus from inception to August 2024. Studies reporting the clinical success, perforation, recurrence, and need for surgery after colonoscopic decompression in ACPO were included. A random-effects inverse-variance model was used to calculate the pooled proportion.
Results: Sixteen studies were included in the final analysis. The pooled rates of success after the first session of colonoscopic decompression and overall success were 78.8% (95%CI: 72.0-85.6) and 91.5% (95%CI: 87.0-96.0), respectively. The first session of colonoscopic decompression had a significantly higher success than the first dose of neostigmine with OR 3.85 (95%CI: 2.00-7.42). The pooled incidence of perforation was 0.9% (95%CI: 0.0-2.0), while recurrence was observed in 17.1% (95%CI: 12.9-21.3) of the patients after clinical success. The pooled rates of surgery in all cases undergoing colonoscopic decompression and those who had a successful procedure were 10.5% (95%CI: 5.0-15.9) and 3.7% (95%CI: 0.3-7.1), respectively. Subgroup analysis, excluding the low-quality studies, did not significantly change the event rates.
Conclusion: Colonoscopic decompression for ACPO is associated with a clinical success rate of > 90% with a perforation rate of < 1%, demonstrating high efficacy and safety.
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http://dx.doi.org/10.5492/wjccm.v14.i3.102733 | DOI Listing |
World J Crit Care Med
September 2025
Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Mumbai 400012, Mahārāshtra, India.
Background: Acute colonic pseudo-obstruction (ACPO) is defined as colonic obstruction without a mechanical or extrinsic inflammatory factor. Colonic decompression is advised for patients with ACPO after the failure of conservative and medical management.
Aim: To systematically review and analyze the efficacy and safety of colonoscopic decompression in ACPO.
J Surg Res
September 2025
Colorectal Surgery Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, West Midlands.
Introduction: Acute colonic pseudo-obstruction is an uncommon but not infrequent encounter among hospitalized patients. The American Society for Gastrointestinal Endoscopy recommended neostigmine first before colonoscopy; however, the Association of Coloproctology of Great Britain and Ireland consensus guidelines in emergency colorectal surgery acknowledge the lack of evidence in the superiority of one approach over the other. This is the first meta-analysis aimed to fill this gap of evidence by including studies comparing neostigmine and colonoscopy in resolving the pseudo-obstruction.
View Article and Find Full Text PDFBr J Surg
April 2025
Colorectal Surgery Unit, Department of Digestive and Emergency Surgery, Grenoble Alpes University Hospital, Grenoble, France.
J Anus Rectum Colon
October 2024
Division of Digestive Surgery, Department of Surgery, Nihon University School of Medicine, Tokyo, Japan.
Objectives: This study was performed to investigate the efficacy of nonoperative treatment of uncomplicated sigmoid volvulus (SV) using a transanal decompression tube (TDT).
Methods: This was a single-center retrospective study in patients with SV treated between 2008 and 2021. For uncomplicated patients, nonoperative decompression of any of four types was performed: decompression with a colonoscope (CS), TDT without CS, TDT with CS (tip in the sigmoid colon), and TDT with CS (tip in the descending colon).
Ann Med Surg (Lond)
October 2024
Faculty of Medicine, University of Kalamoon, Al-Nabk, Syria.