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Importance: Overuse of advanced imaging in the emergency department (ED) contributes to higher costs, reduced efficiency, and crowding. Computed tomographic angiography (CTA) is a recommended first-line diagnostic for acute gastrointestinal bleeding (GIB), yet its increasing use may not always improve detection of active bleeding.
Objective: To evaluate recent trends in CTA use for suspected GIB in the ED and assess changes in diagnostic yield.
Design, Setting, And Participants: This retrospective cohort study included all adult patients who underwent CTA of the abdomen and pelvis for suspected GIB at a 1011-bed urban academic medical center between January 2017 and December 2023.
Exposure: Suspected GIB prompting a CTA order in the ED.
Main Outcomes And Measures: The primary outcome was the annual number and proportion of GIB-related CTAs among all ED computed tomography (CT) examinations. The secondary outcome was the test-positive proportion (diagnostic yield), defined as the percentage of CTAs showing active bleeding or evidence of hemorrhage. All CTAs were interpreted by board-certified emergency radiologists and reviewed by a fellowship-trained emergency radiologist.
Results: Among 954 ED patients (mean [SD] age, 66.7 [6.3] years; 427 female [44.8%]), the number of GIB-related CTA examinations increased from 30 of 32 197 ED CT examinations (0.09%) in 2017 to 288 of 44 423 (0.65%) in 2023. Over the same period, the test-positive proportion declined from 6 of 30 (20.0%) in 2017 to 18 of 288 (6.3%) in 2023. Multivariable analysis showed that more recent calendar year was associated with lower odds of a test-positive examination (OR, 0.84; 95% CI, 0.73-0.96; P = .01), older age with higher odds (OR, 1.02; 95% CI, 1.00-1.04; P = .02), and active cancer with lower odds (OR, 0.35; 95% CI, 0.12-1.00; P = .05).
Conclusions And Relevance: CTA use increased substantially over 7 years while diagnostic yield declined. This trend highlights the need to balance the diagnostic benefit of CTA with interpretation time, radiation exposure, and operational strain. These findings support a need for evidence-based ordering criteria and decision-support tools to help guide CTA use in the ED evaluation of gastrointestinal bleeding.
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http://dx.doi.org/10.1001/jamanetworkopen.2025.29746 | DOI Listing |
Macromol Biosci
September 2025
Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Conventional gelatin's gel-to-sol transition upon heating restricts its utility in biomedical applications that benefit from a gel state at physiological temperatures such as Pluronic F127 and poly(NIPAAm). Herein, we present "rev-Gelatin", a gelatin engineered with reverse thermo-responsive properties that undergoes a sol-to-gel transition as temperature rises from ambient to body temperature. Inspired by the phase dynamics of common materials like candy and ice cubes, whose surfaces soften or partially melt under warming, facilitating inter-object adhesion- rev-Gelatin leverages this concept to achieve fluidity at room temperature for easy injectability.
View Article and Find Full Text PDFJ Vasc Surg Cases Innov Tech
December 2025
Department of Vascular Surgery, Baptish Health, Birmingham, AL.
Subclavian artery-esophageal fistula is a rare but potentially fatal vascular anomaly. Inherent to Downs syndrome, trisomy 21 presents with a variety of rare cardiac and vascular anomalies. Subclavian-esophageal fistulae are rare and often fatal complications of a right-sided aortic arch.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Gastrointestinal Surgery, Jinhua Central Hospital, Jinhua, China.
Background: Chronic intestinal bleeding caused by vascular malformations is uncommon. Locating these small intestinal vascular malformations with precision during surgery remains a challenge. With the rapid development of digital subtraction angiography (DSA), the detection of small intestinal vascular malformations has become easier.
View Article and Find Full Text PDFSurg Case Rep
August 2025
Department of Vascular Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.
Introduction: Abdominal compartment syndrome (ACS) is a serious complication that can occur after endovascular aneurysm repair (EVAR) for ruptured abdominal aortic aneurysm (rAAA). Prompt recognition and appropriate management are crucial to improve patient outcomes.
Case Presentation: An octogenarian with an 11-cm rAAA underwent emergent EVAR due to cardiovascular instability.
J Surg Case Rep
September 2025
Department of Surgery, Faculty of Medicine, University of Colombo, No. 25, Kynsey Road, Colombo 8, Sri Lanka.
Pancreatogastric fistulas are rare but serious complications of chronic pancreatitis that can lead to life-threatening gastrointestinal bleeding due to erosion of nearby blood vessels. We present a case of a 43-year-old man with chronic calcific pancreatitis and a history of alcohol misuse, who experienced recurrent hematemesis and melena over 2 months. Despite multiple endoscopies and transfusions, the bleeding source remained unidentified until imaging revealed a fistulous tract between the pancreas and the posterior gastric wall.
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