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Using Influenza Hospitalization Surveillance Network (FluSurv-NET) data, we established thresholds for weekly hospitalization rate differences to categorize changes. We applied thresholds to National Healthcare Safety Network influenza admissions from the 2022/2023-2023/2024 seasons. This metric identified more large increases and decreases in 2022/2023 and facilitated rapid trend assessment.
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http://dx.doi.org/10.1093/ofid/ofaf460 | DOI Listing |
J Imaging Inform Med
September 2025
Department of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Large language models (LLMs) have been successfully used for data extraction from free-text radiology reports. Most current studies were conducted with LLMs accessed via an application programming interface (API). We evaluated the feasibility of using open-source LLMs, deployed on limited local hardware resources for data extraction from free-text mammography reports, using a common data element (CDE)-based structure.
View Article and Find Full Text PDFVirchows Arch
September 2025
Institute of Pathology, University Hospital Schleswig-Holstein, Kiel, Germany.
Mixed neuroendocrine and non-neuroendocrine neoplasms (MiNEN) represent a heterogeneous group of bidirectionally differentiated epithelial malignancies that are, in most cases, highly aggressive. They are defined by the presence of morphologically distinct, yet clonally related, neuroendocrine and non-neuroendocrine components, each comprising at least 30% of the tumor mass according to current guidelines. Tumors that fall within the differential diagnostic spectrum of MiNEN include amphicrine carcinomas-characterized by the co-expression of neuroendocrine and non-neuroendocrine features within the same tumor cell-as well as conventional carcinomas that lack neuroendocrine morphology but exhibit immunohistochemical expression of neuroendocrine markers.
View Article and Find Full Text PDFEnviron Monit Assess
September 2025
School of Materials Engineering, Changzhou Vocational Institute of Industry Technology, Changzhou, 213000, People's Republic of China.
A multi-indicator framework was developed to resolve multi-source pollution in highly urbanized rivers, demonstrated in the Qinhuai River Basin, Nanjing, China. Water quality index (WQI) stratification was integrated with dissolved organic matter (DOM) fluorescence components, hydrochemical ions, and conventional parameters and analyzed using positive matrix factorization (PMF). Correlation analysis further elucidated source compositions and interactions.
View Article and Find Full Text PDFSci Justice
September 2025
Department of Forensic Science, People's Public Security University of China, Beijing 100038, China. Electronic address:
As a critical frontier in forensic science, the profiling of physical evidence characteristics has garnered substantial attention. This study employed gas chromatography-mass spectrometry (GC-MS) to investigate age-related differences in sebaceous fingermark fatty acid compositions. Fingermark samples from 80 volunteers were analyzed to characterize fatty acid profiles across different age groups.
View Article and Find Full Text PDFJ Med Internet Res
September 2025
Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea, 82 0220721965.
Background: Biological age (BA) is increasingly recognized as a valuable alternative to chronological age (CA) for assessing an individual's health and aging status. However, existing models are based on limited clinical parameters and have not thoroughly integrated morbidity and mortality data.
Objective: This study aimed to develop and validate a novel transformer-based model, referred to as the BA - CA gap model, for BA estimation that incorporates morbidity and mortality information to improve predictive accuracy and enhance clinical use in the early identification of the risk of age-related diseases.