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Social media promotion of harmful products (e.g., combustible tobacco) poses a public health threat. However, strategies that amplify exposure to and engagement with such content remain understudied. This study aims to characterize strategies boosting cigar, little cigar, and cigarillo (CLCC) marketing visibility, referrals, and engagement on Instagram. Using keyword rules, we collected publicly available CLCC-related Instagram posts from CrowdTangle for a six-year period from August 2016 to October 2021. Posts were categorized as commercial (e.g., posts by tobacco brands or vendors) or organic and were coded for consumer engagement (CE) strategies (e.g., presence of prompts to like/share) using a combination of machine learning methods and human coding. Temporal engagement trends were analyzed using metadata. A total of 320,488 CLCC-related public posts were collected, with 44.6% ( = 142,875) identified as overtly commercial. Of these, 33.5% ( = 47,832) contained CE cues, including discounts and giveaways for tagging peers, liking, commenting, or following CLCC brands and spokesperson/influencers accounts, as well as calls to participate in contests and polls. Overtly commercial CE messages consistently garnered more comments per post and likes per post than non-CE commercial posts. There was a significant upward trend in the rate of comments on CE posts, suggesting growing effectiveness in eliciting user interaction. The proliferation of and high level of engagement with cigar-related promotional messages on Instagram demonstrate the need for public health surveillance and regulation of the evolving strategies promoting CLCC marketing exposure, reach, and engagement on social media.
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http://dx.doi.org/10.3390/ijerph22081285 | DOI Listing |
APMIS
September 2025
Department of Chemistry, PSGR Krishnammal College for Women, Coimbatore, Tamil Nadu, India.
Kefir grains offer numerous health benefits, including boosting the immune system, alleviating digestive issues, and enhancing antimicrobial activity. They are rich in beneficial probiotic bacteria that promote gut health and support a balanced intestinal microbiota. "Beta-lactoglobulin (β-lg), a well-known milk protein," is used to create nanofibril structures that can serve as scaffolds.
View Article and Find Full Text PDFJ Pineal Res
September 2025
School of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), School of Tropical Agriculture and Forestry, Hainan University, Sanya, China.
Melatonin, a multifunctional signalling molecule in plants, has been increasingly recognized for its role in improving stress tolerance, regulating hormone signalling, and enhancing crop productivity. Exogenous melatonin application represents a promising strategy to enhance crop productivity under global agricultural challenges. This study aimed to investigate the physiological and molecular mechanisms by which melatonin improves yield in Brassica napus.
View Article and Find Full Text PDFJ Infect Public Health
September 2025
AP-HP, Hospital Bichat - Claude-Bernard, Infectious and Tropical Diseases Department, IAME UMR 1137 INSERM, Université Paris Cité, France; IMEA, Hospital Bichat-Claude Bernard, Paris, France.
Background: Polymedication and comorbidities are frequent in aging people with HIV (PWH) and often associated with elevated incidences of adverse events (AEs) and drug-drug interactions (DDIs). The objective of this study was to evaluate the efficacy, safety and practicality of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF), an antiretroviral (ARV) therapy with limited DDIs, in an elderly virologically-controlled PWH population.
Materials And Methods: This study was prospective, multicentric, single-arm conducted in HIV-1 controlled PWH aged over 65 years who switched from a ritonavir- or cobicistat-boosted containing regimen to B/F/TAF.
J Hazard Mater
September 2025
Department of Civil and Environmental Engineering, Temple University, Philadelphia, PA 19122, United States. Electronic address:
Chlorine dioxide (ClO) has been emerging as an alternative to chlorine for disinfection due to the lower formation of regulated organic disinfection byproducts (DBPs). This pilot-scale study investigated the impacts of ClO pre-oxidation and delayed chlorination on regulated and unregulated DBPs. These included trihalomethanes (THMs), haloacetic acids (HAAs), halonitromethanes (HNMs), chloral hydrate, chlorite, and chlorate.
View Article and Find Full Text PDFBioelectrochemistry
August 2025
Department of General Surgery, Hui Ya Hospital of The First Affiliated Hospital, Sun Yat-Sen University, Huizhou, Guangdong 516081, China. Electronic address:
Human epidermal growth factor receptor-2 (HER-2), a key biomarker in breast cancer, is critical for early diagnosis and prognosis evaluation. In this work, a label-free electrochemical immunosensor was developed for biomarker HER-2 detection based on PtSnCoNi hierarchical dendritic alloyed nanowires (PtSnCoNi HDNWs). These nanowires were synthesized via a co-reduction-triggered anisotropic growth strategy in oleylamine.
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