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Article Abstract

We determined CYP2D6*4 and CYP2D6* genotypes and metabolizer phenotypes in 96 patients with suspected malaria in Venezuela and found intermediate or poor metabolizer phenotypes in ≈25% of cases. Nine of 44 malaria patients had Plasmodium vivax recurrence. Public health authorities should evaluate the benefits of increasing total doses of primaquine for treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407200PMC
http://dx.doi.org/10.3201/eid3109.250316DOI Listing

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