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Recent advancements in the management of inflammatory arthritis have shifted the focus toward patient-centered care, with increasing emphasis on patient education, engagement, and treatment adherence. At the same time, the growing use of imaging techniques offers novel opportunities to enhance communication between healthcare professionals and patients. This review examines current evidence on how visual tools and imaging modalities can improve patient understanding, foster engagement, and strengthen adherence in inflammatory arthritis. Barriers to adherence often arise from low health literacy and entrenched beliefs about illness and medications. However, visual communication has shown promise in addressing these challenges. Research in rheumatoid arthritis (RA), juvenile idiopathic arthritis, and gout suggest that showing personal or illustrative images can increase disease insight, reinforce treatment necessity, and encourage shared decision-making. Among imaging techniques, musculoskeletal ultrasound (MSUS) stands out for its real-time use and interactive potential. Although findings-especially in RA-are encouraging, the overall evidence remains limited, with lack of research in spondyloarthritis and scarce data on long-term outcomes. Further studies are needed to develop standardized protocols and identify patient subgroups most likely to benefit. Ultimately, integrating imaging into patient education may be a valuable strategy to improve care experiences and outcomes in inflammatory arthritis.
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http://dx.doi.org/10.3389/fmed.2025.1630114 | DOI Listing |
Chem Biodivers
September 2025
Zhejiang Provincial Engineering Research Center of New Technologies and Applications for Targeted Therapy of Major Diseases, Laboratory of Anti-Allergy Functional Compounds, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Autoimmune diseases (AIDs), defined by irregularities in immune system function, pose a substantial health challenge worldwide, impacting millions with persistent and frequently debilitating conditions. Conventional treatments, such as glucocorticoid-based immunosuppressive therapies, are associated with notable drawbacks and limitations. In response to these difficulties, recent scientific efforts have increasingly focused on natural compounds as potential therapeutic agents.
View Article and Find Full Text PDFOphthalmol Glaucoma
September 2025
Department of Ophthalmology and Visual Sciences, University of Michigan W.K. Kellogg Eye Center, Ann Arbor, Michigan. Electronic address:
Purpose: To investigate hand function and eye drop instillation success in adults with and without glaucoma.
Design: Cross-sectional pilot study.
Subjects: Adults aged ≥ 65 years with glaucoma who use eye drops daily and adults aged 65+ without glaucoma who do not regularly use eye drops.
Rheumatology (Oxford)
September 2025
Department of Rheumatology, Kochi Memorial Hospital, Kochi, Kochi Prefecture, Japan.
ChemMedChem
September 2025
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103, Leipzig, Germany.
The transcription factor signal transducer and activator of transcription (STAT)4 is a potential target for autoimmune diseases, such as inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, and diabetes mellitus. p-Biphenyl phosphate is reported as an inhibitor of the STAT4 Src homology 2 domain, and it is developed to the phosphonate-based inhibitor Stafori-1. Herein, structure-activity relationships of p-biaryl phosphates against STAT4 and their selectivity profiles against other STAT proteins are reported.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
MS4A4A belongs to the MS4A tetraspan protein superfamily and is selectively expressed by the monocyte-macrophage lineage. In this study, we aimed to evaluate the role of MS4A4A+ macrophages in rheumatoid arthritis (RA) pathogenesis and response to treatment. RNA sequencing and immunohistochemistry of synovial samples from either early treatment-naïve or active chronic RA patients showed that MS4A4A expression positively correlated with synovial inflammation.
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