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Objectives: Noise is a pervasive environmental factor in manufacturing settings and is a well-known cause of noise-induced hearing loss. However, its effects on autonomic nervous system function and cognitive work performance have not been thoroughly investigated. This study aimed to elucidate the impact of high-intensity noise exposure on autonomic activity and cognitive performance using objective physiological and behavioral indicators.
Methods: Task performance was assessed using two 15-minute sessions of the Uchida-Kraepelin test. Autonomic nervous system activity was evaluated through continuous monitoring of heart rate variability (HRV) and measuring salivary amylase activity at three time points: immediately before the first test, between the two test sessions, and immediately after the second test. All measurements were conducted on two separate days under the absence of noise or the presence of 90 dB[A] pink noise.
Results: Exposure to noise significantly increased low-frequency (LF) and the LF / (LF + high-frequency [HF]) ratio. HF and the coefficient of variation of R-R intervals (CVRR) showed no significant change. Salivary amylase activity was also significantly elevated during noise exposure, particularly after task completion. Performance on the Uchida-Kraepelin test revealed a significant decrease in the response volume ratio under noise exposure. The number and rate of incorrect responses remained unchanged.
Conclusion: High-intensity noise exposure activates the sympathetic nervous system and impairs work performance by reducing processing speed while maintaining accuracy. These findings underscore the importance of considering noise not only as an auditory hazard but also as a factor affecting cognitive ergonomics and occupational performance.
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http://dx.doi.org/10.1093/joccuh/uiaf050 | DOI Listing |
Neurology
October 2025
Department of Radiology, Mayo Clinic, Rochester, MN.
Background And Objectives: The relationship between insomnia and cognitive decline is poorly understood. We investigated associations between chronic insomnia, longitudinal cognitive outcomes, and brain health in older adults.
Methods: From the population-based Mayo Clinic Study of Aging, we identified cognitively unimpaired older adults with or without a diagnosis of chronic insomnia who underwent annual neuropsychological assessments (z-scored global cognitive scores and cognitive status) and had quantified serial imaging outcomes (amyloid-PET burden [centiloid] and white matter hyperintensities from MRI [WMH, % of intracranial volume]).
J Neurophysiol
September 2025
Department of Radiology, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Heping District, Shenyang 110004, China.
Neonatal hypoxic-ischemic encephalopathy (HIE) is a significant cause of developmental disorders and permanent central nervous system damage, with functional recovery closely linked to myelin sheath integrity. This study aimed to analyze the expression of pH and the voltage-gated proton channel (Hv1) in the brains of neonatal pigs with HIE at various time points, alongside changes in myelin-related proteins. MRI was employed to localize the basal ganglia and assess pH changes post-hypoxia-ischemia, while immunofluorescence staining was used to evaluate Hv1, myelin basic protein (MBP), myelin oligodendrocyte glycoprotein (MOG), and myelin-associated glycoprotein (MAG).
View Article and Find Full Text PDFJ Neurophysiol
September 2025
Max Planck Research Group Pain Perception, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Repetition suppression, the reduced neural response upon repeated presentation of a stimulus, can be explained by models focussing on bottom-up (i.e. adaptation) or top-down (i.
View Article and Find Full Text PDFSci Adv
September 2025
Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
The locus coeruleus-norepinephrine (LC-NE) system regulates arousal and awakening; however, it remains unclear whether the LC does this in a global or circuit-specific manner. We hypothesized that sensory-evoked awakenings are predominantly regulated by specific LC-NE efferent pathways. Anatomical, physiological, and functional modularities of LC-NE pathways involving the mouse basal forebrain (BF) and pontine reticular nucleus (PRN) were tested.
View Article and Find Full Text PDFSci Adv
September 2025
School of Electrical and Electronic Engineering, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Brain-computer interfaces (BCIs) enable direct communication between the brain and computers. However, their long-term functionality remains limited due to signal degradation caused by acute insertion trauma, chronic foreign body reaction (FBR), and biofouling at the device-tissue interface. To address these challenges, we introduce a multifunctional surface modification strategy called targeting-specific interaction and blocking nonspecific adhesion (TAB) coating for flexible fiber, achieving a synergistic integration of mechanical compliance and biochemical stability.
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