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http://dx.doi.org/10.1111/resp.70108 | DOI Listing |
Background: Central centrifugal cicatricial alopecia (CCCA) is a scarring alopecia primarily affecting Black women. To date, there are no standardized treatment regimens or approved medications for the treatment of CCCA. This single-center, open-label, clinical study investigated the efficacy of apremilast in the treatment of mild to moderate vertex-predominant CCCA.
View Article and Find Full Text PDFRespirology
September 2025
Department of Respiratory & Sleep Disorders Medicine, Western Health, Footscray, Victoria, Australia.
J Endovasc Ther
August 2025
Vascular and Interventional Physicians, Gainesville, FL, USA.
The evolution from critical limb ischemia to chronic limb-threatening ischemia (CLTI) necessitates a reevaluation of clinical trial endpoints. Traditional measures like hemodynamic indices and lesion patency inadequately reflect CLTI complexity or patient-centered outcomes. This article explores the limitations of conventional endpoints and proposes a modified definition of clinically-driven target lesion (TL) revascularization (CD-TLR) that addresses inflow, TL, and outflow disease.
View Article and Find Full Text PDFRespirology
August 2025
Department of Respiratory & Sleep Medicine, The Alfred Hospital, Melbourne, Victoria, Australia.
J Coll Physicians Surg Pak
August 2025
Department of Plastic Surgery, Mayo Hospital, King Edward Medical University, Lahore, Pakistan.
Objective: To determine the effect of minced skin grafting on complete healing of the donor site and cosmetic appearance in different skin phototypes.
Study Design: Case series. Place and Duration of the Study: Department of Plastic Surgery, Mayo Hospital, King Edward Medical University, Lahore, Pakistan, from June 2021 to April 2022.