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Lower limb amputation greatly affects quality of life by restricting functional mobility. Despite advancements in prosthetic design, powered transtibial prostheses still have limitations in user control and adaptability to dynamic environments. This research presents a comparative analysis between a novel electromyography (EMG)-driven variable impedance controller (VIC) and a hybrid controller (HC) that integrates a volitional EMG-driven musculoskeletal model with a finite-state machine impedance controller. A Hill-type muscle model was used to model the gastrocnemius and tibialis anterior muscles. Biomechanical testing was conducted with a transtibial amputee to assess the controllers' performance across various tasks, including ambulation on level ground, stairs, and ramps, using EMG signals from the residual limb. Results demonstrated that the VIC provided more repeatable performance, perceived control, and power output. Notable effect sizes for peak power, observed in ramp ascent (Cohen's d $= -1.04$ ) and high-speed level ground walking (Cohen's d $= -2.92$ ), illustrate robust differences in joint-level output even when walking speeds and cadences were comparable. The greater predictability of the VIC led the user to feel more in control and comfortable throughout the various activities. On the other hand, the HC controller performed better in enabling more seamless transitions between gait subphases, particularly during stair ascent, which led to a significantly higher ROM ( $18.63~\pm ~1.53$ deg vs. $12.43~\pm ~1.86$ deg) and nearly double peak power compared to the VIC. This comparison lays the groundwork for future research into optimizing EMG-based control strategies that adapt to both biomechanical demands and user preferences.
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http://dx.doi.org/10.1109/TNSRE.2025.3602296 | DOI Listing |
Cureus
August 2025
Physical Medicine and Rehabilitation, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Background: Lower limb amputation (LLA) significantly affects mobility and increases fall risk, particularly in individuals with higher-level amputations and lower functional capacity. Effective tools to assess fall risk are essential in rehabilitation.
Objective: This study was conducted at the Department of Physical Medicine and Rehabilitation, Coimbra University Hospital (HUC), Coimbra, Portugal.
Prosthet Orthot Int
April 2025
Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.
Background: Prosthetic alignment is a critical factor in the functionality and comfort of transtibial prostheses, which are still based on amputee's feedback prosthetist experience and clinical judgment. Proper alignment involves a series of procedures, including bench, static, and dynamic alignment, each contributing to the overall success of the prosthesis.
Objective: This cross-sectional study aims to explore transtibial prosthetic alignment practices among prosthetists in Malaysia, Jordan, and Saudi Arabia, focusing on the associations of demographic data, occupational status, and knowledge on common prosthetic alignment guidelines.
Sensors (Basel)
August 2025
Department of Robotics and Technical Tools of Automation, Satbayev University, Almaty 050013, Kazakhstan.
This paper presents the development, modeling, and analysis of an autonomous active ankle prosthesis with two degrees of freedom (2-DoF), designed to reproduce movements in the sagittal (dorsiflexion/plantarflexion) and frontal (inversion/eversion) planes in order to enhance the stability and naturalness of the user's gait. Unlike most commercial prostheses, which typically feature only one active degree of freedom, the proposed device combines a lightweight mechanical design, a screw drive with a stepper motor, and a microcontroller-based control system. The prototype was developed using CAD modeling in SolidWorks 2024, followed by dynamic modeling and finite element analysis (FEA).
View Article and Find Full Text PDFIEEE Trans Neural Syst Rehabil Eng
September 2025
This study investigates the structural and functional characteristics of residual muscles in transtibial amputees (TTAs) to improve electromyography (EMG)-based prosthetic control. Using ultrasonography, we measured the thickness of the Tibialis Anterior (TA), Peroneus Longus (PL), Gastrocnemius Medialis (GM), and Lateralis (GL) at rest and during contraction. Surface EMG was employed to assess muscle activation patterns, co-contraction levels, and accuracy in modulating submaximal contractions at 25%, 50%, and 75% of maximum voluntary contraction (MVC).
View Article and Find Full Text PDFPhys Ther
August 2025
New York Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, United States.
Importance: Lower extremity amputation (LEA) is a worldwide public health problem leading to large disability burdens and health care costs. After LEA, prostheses improve functional mobility and quality-of-life. However, health care costs are high and prosthetic provision worldwide unknown.
View Article and Find Full Text PDF