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Introduction: Situs inversus totalis (SIT) is a rare congenital condition in which the major visceral organs are mirrored from their normal positions. Appendicitis in patients with SIT can be diagnostically challenging due to the atypical location of abdominal pain, typically presenting on the left side. Foreign body impacted appendicitis is a rare occurrence.
Case Presentation: We present a case of a 10-year-old boy presented to the emergency room with complaints of abdominal pain in the left lower abdomen. Acute appendicitis with an impacted foreign body in the lumen of the appendix was found in ultrasonography (USG). Chest X-ray showed dextrocardia and fundic gas under the right hemidiaphragm and the liver shadow on the left illustrating SIT. The patient underwent an urgent midline laparotomy, revealing a left iliac fossa appendix consistent with situs inversus. The inflamed appendix contained a palpable foreign body. The appendix was excised, revealing a sewing machine pin approximately 5 cm in length lodged in the appendiceal lumen.
Discussion: Situs inversus totalis is a rare condition in which the orientation of visceral organs mirrors the normal anatomy. Abdominal pain is one of the most frequent chief complaints among patients in the Emergency department, with appendicitis being the most common surgical condition diagnosed. Left-sided lower abdominal pain can be the presentation of appendicitis in situs inversus totalis. Usual presentation is right-sided pain so doctors do not consider left-sided lower abdominal pain as differential diagnosis of acute appendicitis making atypical presentation difficult to diagnose. Failure to consider this anatomical variation could delay diagnosis, leading to misinterpretation of symptoms and unnecessary or inappropriate investigations.
Conclusion: In cases of left lower quadrant pain with dextrocardia and right-sided gastric gas bubble on chest X-ray should be thought of acute appendicitis. USG or computed tomography abdomen must be done to diagnose appendicitis with an impacted foreign body in SIT.
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http://dx.doi.org/10.1097/MS9.0000000000003369 | DOI Listing |
Front Oncol
August 2025
Department of Gastrointestinal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University Yuexi Hospital, Xinyi, China.
Situs inversus totalis (SIT) is a rare congenital condition characterized by a complete reversal of the internal organ arrangement, presenting significant surgical challenges. While previous cases of colorectal cancer in SIT patients have been reported, cases involving sigmoid colon cancer are sporadic. Here, we present the case of a 68-year-old female with sigmoid colon cancer and SIT.
View Article and Find Full Text PDFFront Pediatr
August 2025
Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, University of London, London, United Kingdom.
Emerging evidence suggests a potential link between maternal SARS-CoV-2 infection during early pregnancy and the development of congenital heart defects (CHD) in offspring. Although vertical transmission of SARS-CoV-2 is rare, the virus has been associated with placental complications and increased maternal morbidity. Recent studies from China report increased rates of CHD and anomalies such as situs inversus when infection occurs during gestational weeks 4-6, a critical window for cardiac development.
View Article and Find Full Text PDFAnn Med Surg (Lond)
September 2025
Devdaha Medical College, Rupandehi, Nepal.
Introduction: Situs inversus totalis is an uncommon congenital disease characterized by the full transposition of thoracic and abdominal organs. Sigmoid volvulus, an unusual but potentially catastrophic cause of major bowel obstruction, is rarely associated with Situs inversus.
Case Presentation: A 76-year-old male presented with abdominal pain and obstipation for 5 days.
J Surg Case Rep
August 2025
Department of General Surgery, Hera General Hospital, Al Madinah Al Munawarah Rd, Makkah 24227, Saudi Arabia.
Situs inversus totalis (SIT) is a rare congenital anomaly involving mirror-image reversal of thoracic and abdominal organs, which may complicate the diagnosis and management of acute abdominal conditions due to atypical symptom localization. This report describes a 23-year-old male who presented with lower abdominal pain and vomiting. Clinical examination revealed tenderness in the left iliac fossa and laboratory findings showed leukocytosis.
View Article and Find Full Text PDFJ Med Case Rep
September 2025
Tikur Anbessa Hospital, Addis Ababa, Ethiopia.
Background: Situs inversus totalis is an uncommon congenital condition characterized by the complete reversal of internal organ placements from their usual orientation. This syndrome presents challenges in both diagnostic and surgical care owing to the anatomical reversal, with an incidence rate of around 1 in 5000 to 20,000 infants.
Case Presentation: A 50-year-old Asian Sindhi Ayan female patient with well-managed hypertension presented with intermittent cramp-like discomfort in the upper left region of her abdomen, which exacerbated after consuming fatty foods, accompanied by feelings of nausea and vomiting.