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Aims: To evaluate in a range of abattoirs in Australia, the effect of a fully nylon-lined, noise-reducing restraint box on animal handling practices during pre-slaughter handling with a view to improving animal welfare by facilitating the movement of animals through the race into restraint for stunning.
Methods: Data were collected from eight meat processors in Australia, with pre- and post-installation data available for four, and post-installation data available for all eight. Two separate analyses were conducted: one to compare pre- and post-installation data to evaluate the impact of the noise-reducing restraint box on animal handling practices, and another to investigate the variability between processors in the handling interventions required post-installation of the noise-reducing restraint box. Individual handling parameters (physical intervention/aid or noise, such as whistling or hitting the race to help animals move forward) were measured for each processor.
Results: Overall, there was a noticeable reduction in almost all handling parameters, with a few exceptions. For both physical and noise interventions, there was a significant interaction between treatment and processors (p < 0.01). Cattle received less handling aid post-installation compared to pre-installation (marginal mean (MM) number of events = 1.64 (95% CI = 1.47-1.84) . 3.14 (95% CI = 2.90-3.41); p < 0.01). However, handling noise was increased post-installation compared to pre-installation (MM = 1.08 (95% CI = 0.94-1.22) . 0.70 (95% CI = 0.61-0.81); p < 0.01). Thus, the use of the noise-reducing restraint box led to a reduction in the use of physical handling methods, but there was an increase in the use of other less stressful forms of coercion such as staff vocalisations. Post-installation analysis showed that handling interventions (aid and noise) varied significantly among processors (p < 0.05).
Conclusions And Clinical Relevance: The noise-reducing restraint box reduced the need for physical coercion, potentially improving animal movement through the race and offering improvements in production efficiency, animal welfare and staff morale. However, variation between processors indicates that there are other factors influencing system flow and animal welfare.
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http://dx.doi.org/10.1080/00480169.2025.2542370 | DOI Listing |
Surg Endosc
September 2025
Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Introduction: Large abdominal wall defects are increasingly repaired robotically using bilateral component separation and myofascial release. Existing studies on complication rates and operative variables fail to capture the patient experience, creating a gap in our understanding of how transversus abdominis releases (TAR) impact quality of life (QoL). Using two validated hernia-specific tools, the Hernia-Related Quality-of-life Survey (HerQLes) and the Carolinas Comfort Scale (CCS), we compared improvements in patient-reported outcomes between the two approaches.
View Article and Find Full Text PDFIBRO Neurosci Rep
December 2025
Department of Biological Sciences, Faculty of Science, University of Maroua, P.O. Box 814, Maroua, Cameroon.
Depression is a highly prevalent neuropsychiatric disorder globally, and its increasing incidence is thought to be mediated by the growing exposure to stressful life events and conditions. is widely used in traditional medicine to treat fever, pain, epilepsy, and depression. This study aimed at evaluating the antidepressant effect of aqueous extract (CF) using the chronic physical restriction stress (CRS) model on male and female rats.
View Article and Find Full Text PDFNeuroscience
August 2025
Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269, USA; Institute for Systems Genomics, University of Connecticut, Storrs, CT 06269, USA; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA; Department of Psychological Sciences,
Disruptions in the endocannabinoid system (ECS) and norepinephrine/epinephrine (NE/E) system are individually linked to stress-related neuropsychiatric disorders, but their interaction in shaping stress responses remains unclear. We investigated the role of the ECS's primary receptor, cannabinoid type-1 receptor (CB1R), in NE/E-producing neurons using anatomical, behavioral, and physiological analyses in a conditional knockout mouse model (Cnr1), in which the Cnr1 gene-encoding CB1R-was selectively deleted in dopamine beta-hydroxylase-expressing cells. In situ hybridization in control mice revealed Cnr1 is broadly expressed in medullary C1/A1 and C2/A2 and sparsely in the locus coeruleus, marking the first cell-type-specific characterization of Cnr1 in brainstem catecholaminergic populations.
View Article and Find Full Text PDFGenes (Basel)
August 2025
Department of Biomedical Sciences, School of Biological and Environmental Sciences, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda 669-1330, Japan.
Background: DEAD/H box 5 (DDX5) serves as a transcriptional coactivator for several transcription factors including E2F1, the primary target of the tumor suppressor pRB. E2F1 physiologically activated by growth stimulation activates growth-related genes and promotes cell proliferation. In contrast, upon loss of pRB function due to oncogenic changes, E2F1 is activated out of restraint by pRB (deregulated E2F1) and stimulates tumor suppressor genes such as , which activates the tumor suppressor p53, to suppress tumorigenesis.
View Article and Find Full Text PDFN Z Vet J
August 2025
Agriculture and Food, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Armidale, NSW, Australia.
Aims: To evaluate in a range of abattoirs in Australia, the effect of a fully nylon-lined, noise-reducing restraint box on animal handling practices during pre-slaughter handling with a view to improving animal welfare by facilitating the movement of animals through the race into restraint for stunning.
Methods: Data were collected from eight meat processors in Australia, with pre- and post-installation data available for four, and post-installation data available for all eight. Two separate analyses were conducted: one to compare pre- and post-installation data to evaluate the impact of the noise-reducing restraint box on animal handling practices, and another to investigate the variability between processors in the handling interventions required post-installation of the noise-reducing restraint box.