Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1053/j.gastro.2025.08.016 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
An Unusual Cause of Hypolipidemia With Cirrhosis in a Father-Son Pair.
Gastroenterology
August 2025
Center for Fatty Liver, Department of Gastroenterology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Key Lab of Pediatric Gastroenterology and Nutrition, Shanghai, China. Electronic address:
Background: Familial combined hypolipidaemia is a condition characterised by very low concentrations of circulating very-low-density lipoprotein (VLDL), low-density lipoprotein cholesterol (LDL), and high-density lipoprotein cholesterol (HDL). It is thought that low LDL/combined hypolipidaemia can protect from cardiovascular disease (CVD), but this is not what we found in a case we present.
Objective: We report on a 57-years-old male patient with combined hypolipidaemia who presented with premature peripheral vascular disease.
Using human genetics to discover new therapeutic targets for plasma lipids.
J Intern Med
November 2016
Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Genetic variation arises through multiple different alleles that vary in frequency and severity of effect. Mutations that give rise to Mendelian disorders, such as the LDL receptor (LDLR) mutations that result in familial hypercholesterolaemia, are efficiently winnowed from the population by purifying selection and are almost inevitably rare. Conversely, alleles that are common in the population (such that homozygotes for the minor allele are present even in modest sample sizes) typically have very modest phenotypic effects.
View Article and Find Full Text PDFAn unusual cause of chyluria after radiofrequency ablation of a renal cell carcinoma: a case report.
J Med Case Rep
July 2011
Clinical Radiology Department, St James's University Hospital, Leeds Teaching Hospitals Trust, Leeds, LS9 7TF, UK.
Introduction: This report highlights a rare cause of chyluria occurring after radiofrequency ablation of a renal cell carcinoma. The condition requires a high index of suspicion, as it may not be diagnosed routinely on imaging follow-up after treatment. As chyluria can vary from no symptoms to hypoproteinemia, hypolipidemia and impaired immune function, prompt diagnosis will allow timely management of symptoms.
View Article and Find Full Text PDFHypolipidaemia is not always indicating liver dysfunction. A review of primary and secondary high density lipoprotein and low density lipoprotein deficiencies.
Minerva Med
December 2006
Department of Endocrinology, University Hospital of Ioannina, Ioannina, Greece.
Hypolipidaemias can be either primary due to several genetic defects altering the serum concentration of lipoproteins, or secondary resulting from various disorders such as liver disease, malabsorption, malnutrition, malignancy, hyperthyroidism and immunoglobulin disorders. We present a review of the current knowledge regarding the various causes of hypolipidaemias. Our aim is to emphasize on the different mechanisms, apart from deranged liver synthetic function, that are responsible for unusually low levels of cholesterol and on the disorders that need to be considered during the investigation of hypolipidaemia.
View Article and Find Full Text PDF