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Objective: To analyze maternal characteristics, induction methods, and their association with delivery outcomes in women undergoing induction of labor (IOL).
Methods: We conducted a retrospective analysis of 947 women who underwent IOL at the Princess Royal University Hospital during the period from April 2018 to April 2019. Out of 4316 total births during the study period, 947 women underwent IOL and were included in our analysis. Statistical analyses were performed using STATA version 17.0, with appropriate statistical tests including χ tests, t tests, and logistic regression models.
Results: The overall vaginal delivery rate was 71.7% (n = 679) (51.4% (n = 487) spontaneous, 20.3% (n = 192) instrumental), with 28.3% (n = 268) requiring cesarean section. Nulliparity was significantly associated with higher cesarean rates compared with multiparity (39.1% (n = 101/259) versus 24.3% (n = 167/688), P < 0.001; odds ratio [OR] 2.01, 95% confidence interval [CI] 1.52-2.66). Women with a body mass index (BMI; calculated as weight in kilograms divided by the square of height in meters) of 30 or greater had significantly higher cesarean section rates than those with normal BMI (35.4% (n = 91/257) versus 23.2% (n = 94/406), P < 0.001; OR 1.82, 95% CI 1.34-2.47). The mean time from induction to birth was 28.4 h (range 1.05-71.78 h). Logistic regression analysis identified parity (OR 0.61, 95% CI 0.49-0.76), BMI (OR 1.06, 95% CI 1.03-1.09), and maternal age (OR 1.03, 95% CI 1.01-1.05) as independent predictors of cesarean delivery.
Conclusion: Maternal characteristics, particularly parity and BMI, significantly influence delivery outcomes following IOL. Understanding these factors can help optimize patient selection, counseling, and management strategies for IOL. Although statistically significant associations were identified, the clinical significance of some factors requires careful interpretation in individual patient counseling.
Registration Number: Clinical Audit Committee Registration Number: 615/23052025.
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http://dx.doi.org/10.1002/ijgo.70491 | DOI Listing |
Exp Physiol
September 2025
Faculty of Medicine, Department of Physiology, Bursa Uludağ University, Bursa, Türkiye.
Autism spectrum disorders (ASD) are neurodevelopmental pathologies. Investigating both sexes is crucial for understanding sex-specific manifestations of ASD. This study aims to examine ASD-like behaviours and metabolic alterations in male and female rats prenatally exposed to valproic acid (VPA).
View Article and Find Full Text PDFVaccine
September 2025
School of Pharmacy and Biomedical Sciences, University of Portsmouth, United Kingdom; ICAP, Columbia University, Lusaka, Zambia; Africa Centre for Inclusive Health Management, Stellenbosch University, Stellenbosch 7600, South Africa; School of Health Systems & Public Health, University of Pretoria,
While maternal influences on childhood immunization have been extensively studied in sub-Saharan Africa (SSA), paternal socioeconomic factors remain underexplored despite their potential impact on vaccination outcomes. This systematic review and meta-analysis aimed to synthesize current evidence on the influence of paternal characteristics on full childhood immunization status in SSA. A comprehensive literature search was conducted in PubMed, Google Scholar, Embase, and Scopus for studies published between January 2014 and March 2025.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
September 2025
Department of Obstetrics and Gynaecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan, Republic of China; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan, Republic of China. Electronic address:
Objective: Endometriosis is a chronic gynaecological condition affecting reproductive-aged women. It has been associated with infertility and potential risks for adverse pregnancy outcomes, although population-level evidence remains limited.
Methods: This retrospective cohort study, including 147,950 pregnant women aged 20-45 years, used nationwide population-based data to compare the outcomes between women with (n = 11,400) and without (n = 136,550) endometriosis between 2000 and 2021.
JMIR Serious Games
September 2025
Global Health Institute, American University of Beirut, PO Box 11-0236, Riad El Solh, Beirut, 1107 2020, Lebanon, 961 3047578.
Background: High maternal morbidity and mortality rates globally, especially in low-income and lower-middle-income countries, highlight the critical role of skilled health care providers (HCPs) in preventing pregnancy-related complications among disadvantaged populations. Lebanon, hosting over 1.5 million refugees, is no exception.
View Article and Find Full Text PDFBraz Oral Res
September 2025
Universidade Federal de Minas Gerais - UFMG, School of Dentistry, Department of Restorative Dentistry, Belo Horizonte, MG, Brazil.
This study aimed to determine the prevalence and provide an overview of Down syndrome and child- and mother-associated factors in Brazil from 2010 to 2020. This was a cross-sectional study including epidemiological characteristics related to live births of individuals with and without Down syndrome using the Brazilian government website. The average prevalence of Down syndrome in Brazil was approximately 30.
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