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Objectives: To compare low-value computed tomography (CT) use during pediatric emergency department (ED) visits by hospital type and physician specialty.
Methods: Repeated cross-sectional study using linked databases from Ontario, Canada. We reviewed pediatric ED discharges from 2010 to 2019 for 5 diagnoses with recommendations against routine CT use: abdominal pain, constipation, concussion, seizure, and headache. We evaluated CT use by hospital type (pediatric academic, adult academic, community with and without pediatric consultation) and provider specialty [pediatric emergency medicine (PEM), emergency medicine (EM), family medicine + EM, family medicine, pediatrician], using multivariable logistic regression, adjusting for patient, ED, and physician characteristics.
Results: We included 599,948 pediatric ED discharges [mean (SD) age 10.8 y (5.3); 55.4% females]: 5000 (1.2%) discharges for abdominal diagnoses included a CT, and 21,398 (11.4%) discharges for neurological diagnoses included a CT. Children had an increased adjusted odds ratio [aOR (95% CI)] of receiving a CT at all hospital types compared with pediatric academic hospitals: adult academic hospitals ranging from 1.10 (1.01 to 1.21) for headache to 3.46 (1.89 to 6.36) for constipation, community hospitals with pediatric consultation ranging from 1.54 (1.45 to 1.63) for concussion to 3.74 (2.38-5.90) for constipation, and community hospitals without pediatric consultation ranging from 1.24 (1.15 to 1.33) for concussion to 2.29 (1.36 to 3.87) for constipation. Those patients seen by nonpediatric providers (EM, family medicine + EM, family medicine) were more likely to receive CT scans than PEM physicians for all diagnoses.
Conclusions: Low-value CT use was higher among children treated in nonpediatric EDs and by nonpediatric providers. Improvement initiatives should target specific hospital types and specialties.
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http://dx.doi.org/10.1097/PEC.0000000000003473 | DOI Listing |
Nephrol Dial Transplant
September 2025
Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Background: We investigated circulating protein profiles and molecular pathways among various chronic kidney disease (CKD) etiologies to study its underlying molecular heterogeneity.
Methods: We conducted a proteomic biomarker analysis in the DAPA-CKD trial recruiting adults with and without type 2 diabetes with an eGFR of 25 to 75 mL/min/1.73m2 and a UACR of 200 to 5000 mg/g.
JMIR Res Protoc
September 2025
Institute of Higher Education and Research in Healthcare, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Background: In pediatric intensive care units, pain, sedation, delirium, and iatrogenic withdrawal syndrome (IWS) must be managed as interrelated conditions. Although clinical practice guidelines (CPGs) exist, new evidence needs to be incorporated, gaps in recommendations addressed, and recommendations adapted to the European context.
Objective: This protocol describes the development of the first patient- and family-informed European guideline for managing pain, sedation, delirium, and IWS by the European Society of Paediatric and Neonatal Intensive Care.
JAMA Netw Open
September 2025
School of Rehabilitation Science, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Importance: The cost-effectiveness of adding early in-bed cycling to usual physiotherapy among adults receiving mechanical ventilation in the intensive care unit (ICU) compared with usual physiotherapy alone is unknown.
Objective: To evaluate the cost-effectiveness of in-bed cycling plus usual physiotherapy compared with usual therapy alone in the Critical Care Cycling to Improve Lower Extremity Strength (CYCLE) randomized clinical trial.
Design, Setting, And Participants: This trial-based economic evaluation with a 90-day time horizon compared early cycling plus usual physiotherapy vs usual physiotherapy alone from a societal perspective.
JAMA Pediatr
September 2025
Department of Family and Community Medicine, Chung Shan Medical University Hospital, School of Medicine, Chung Shan Medical University College of Medicine, Taichung, Taiwan.
Jpn J Ophthalmol
September 2025
Department of Medical Education Studies, International Research Center for Medical Education, Graduate School of Medicine, The University of Tokyo, Bunkyō, Tokyo, Japan.
Purpose: To examine the associations between work-family conflict, implicit gender bias, and turnover intention among hospital ophthalmologists.
Study Design: Cross-sectional study.
Methods: We conducted a web-based questionnaire survey between January and February 2024.