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Why are there so few pathogens, and what determines their emergence? The ecological and evolutionary forces of host availability, geographic exposure, and microbial innovation will shape future human diseases.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370116 | PMC |
http://dx.doi.org/10.1371/journal.pbio.3003329 | DOI Listing |
Ecohealth
September 2025
Graduate Degree Program in Ecology, Colorado State University, Fort Collins, CO, USA.
Batrachochytrium dendrobatidis (Bd) is a fungal pathogen responsible for dramatic declines of amphibian populations around the world. Experimental exposure studies have documented differences in host susceptibility to Bd, but variation in study designs may limit our ability to compare inferences across studies. Using laboratory-maintained pathogen cultures that may lose virulence over time (i.
View Article and Find Full Text PDFJ R Soc Interface
September 2025
UK Centre for Ecology & Hydrology, Wallingford, Oxfordshire, UK.
Severe fever with thrombocytopaenia syndrome virus (SFTSV) was identified by the World Health Organization as a priority pathogen due to its high case-fatality rate in humans and rapid spread. It is maintained in nature through three transmission pathways: systemic, non-systemic and transovarial. Understanding the relative contributions of these transmission pathways is crucial for developing evidence-informed public health interventions to reduce its spillover risks to humans.
View Article and Find Full Text PDFBiol Lett
September 2025
Evolutionary Animal Ecology, University of Bayreuth, Bayreuth, Germany.
Theoretical and empirical considerations suggest that relatedness can have complex effects on social life. While high relatedness may promote sibling cooperation and altruism through indirect fitness benefits, it can also intensify competition if siblings share similar needs and competitive strategies. Moreover, low genetic diversity in highly related groups may heighten susceptibility to pathogens.
View Article and Find Full Text PDFJ Hum Evol
September 2025
Sustainability Solutions Research Lab, University of Pannonia, Egyetem utca 10, H-8200, Veszprém, Hungary. Electronic address:
Denisovans contributed notably to the genomes of present-day East and Southeast Asians. However, the relationship between the inhabited paleohabitats and the adaptive genetic traits related to infections in modern humans remains underexplored. This study uses geospatial techniques to analyze climatic factors associated with three Denisovan archaeological sites linked to nine specimens.
View Article and Find Full Text PDFCrit Rev Microbiol
September 2025
Austrian Competence Centre for Food and Feed Quality, Safety and Innovation, FFoQSI GmbH, Tulln, Austria.
Foodborne illness is a critical food safety and public health concern, often resulting from contamination events by resident pathogens in food processing environments (FPEs). , the causative agent of listeriosis, can persist in FPEs over long time periods. Despite rigorous research on the phenotypic and genotypic traits of , no clear pattern has arisen to explain why some strains are able to persist.
View Article and Find Full Text PDF