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Research on pediatric mental health treatment outcomes require continued participant engagement typically involving the caregivers; however, these studies report high rates of attrition. To increase participant retention, an understanding of participants' experiences that influence their participation is necessary. The current study employed qualitative methods to understand the reasons behind participation of parents enrolling in pediatric longitudinal mental health research targeting their child's mental health. Participants were recruited from a longitudinal study that provided mental health resources to families. Data from 49 parent interviews were analyzed using interpretive description, which generated two themes: influential factors behind parent enrollment and factors impacting retention or attrition. Our findings inform the content and dissemination of recruitment material targeting parent participation in youth mental health research. Further, our findings may inform what information related to the study (e.g., participant responses) should be provided to participants and how dissemination of findings may increase future participation.
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http://dx.doi.org/10.1007/s10578-025-01894-4 | DOI Listing |
Eat Disord
September 2025
Center for Eating and feeding Disorders Research (CEDaR), Psychiatric Center Ballerup, Mental Health Services in the Capital Region of Denmark.
Proc Natl Acad Sci U S A
September 2025
Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240.
Major depressive disorder affects millions worldwide, yet current treatments require prolonged administration. In contrast, ketamine produces rapid antidepressant effects by blocking spontaneous N-Methyl-D-Aspartate (NMDA) receptor signaling, which lifts the suppression of protein synthesis and triggers homeostatic synaptic plasticity. Here, we identify a parallel signaling pathway involving metabotropic glutamate receptor 5 (mGluR5) that promotes rapid antidepressant-like effects.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Lübeck, Lübeck, Germany.
Importance: Patients with inflammatory rheumatic diseases (IRDs) frequently experience psychological distress; however, access to psychological support remains limited.
Objective: To investigate the effectiveness of a digital psychological intervention for individuals with IRDs.
Design, Setting, And Participants: Participants aged 18 years or older were recruited across Germany between February 22 and June 4, 2024, if they had been diagnosed with rheumatoid arthritis, psoriatic arthritis, or systemic lupus erythematosus and reported psychological distress and reduced quality of life.
J Gambl Stud
September 2025
Department of Psychology and Azrieli Israel Center for Addiction and Mental Health, The Hebrew University of Jerusalem, Jerusalem, Israel.
Research suggests that Problem Gambling (PG) may result from maladaptive emotional regulation strategies aimed at escaping emotions and stress caused by negative life events and trauma. The current study, aimed to examine the effect of exposure to the mass trauma of October 7, 2023 terror attack and the consequent Swords of Iron war in Israel, and difficulties in emotional regulation on PG. We utilized longitudinal data of self-reports in the Problem Gambling Severity Index collected before the terror attack (April 2022) and during the Swords of Iron war (December 2023, March 2024, June 2024; N = 899) from a large sample of adult Jewish Israelis.
View Article and Find Full Text PDF