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Intro: The prioritization of topics for evidence synthesis is crucial for maximizing the relevance and impact of systematic reviews. This article introduces a comprehensive toolkit designed to facilitate a structured, multi-step framework for engaging a broad spectrum of stakeholders in the prioritization process, ensuring the selection of topics that are both relevant and applicable.
Methods: We detail an open-source framework comprising 11 coherent steps, segmented into scoping and Delphi stages, to offer a flexible and resource-efficient approach for stakeholder involvement in research priority setting.
Results: The toolkit provides ready-to-use tools for the development, application, and analysis of the framework, including templates for online surveys developed with free open-source software, ensuring ease of replication and adaptation in various research fields. The framework supports the transparent and systematic development and assessment of systematic review topics, with a particular focus on stakeholder-refined assessment criteria.
Conclusion: Our toolkit enhances the transparency and ease of the priority-setting process. Targeted primarily at organizations and research groups seeking to allocate resources for future research based on stakeholder needs, this toolkit stands as a valuable resource for informed decision-making in research prioritization.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362723 | PMC |
http://dx.doi.org/10.1002/cesm.70039 | DOI Listing |
J Neuroimaging
September 2025
Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Background And Purpose: To review the existing evidence on multiple timepoint assessments of optic nerve sheath diameter (ONSD) as an indicator of intraindividual variation of intracranial pressure (ICP).
Methods: A systematic search identified studies assessing intraindividual variation in ICP through multiple timepoint measurements of ONSD using ultrasonography. Meta-analysis of studies assessing intraindividual correlation coefficients between ONSD and ICP was performed using a random effects model, and we calculated the weighted correlation coefficient for the expected change in ICP associated with variations in ONSD.
Pediatr Blood Cancer
September 2025
Centre for Reviews and Dissemination, University of York, York, UK.
Acute leukaemias are the commonest cancers in children and young people (CYP). Off-treatment surveillance is assumed to improve relapse detection, but whether this affects subsequent survival and quality of life is unclear. This systematic review searched 13 databases and two trial registries in December 2022.
View Article and Find Full Text PDFJ Dent Educ
September 2025
Department of Oral and Maxillofacial Surgery, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, P. R. China.
Background: Virtual reality (VR) and artificial intelligence (AI) technologies have advanced significantly over the past few decades, expanding into various fields, including dental education.
Purpose: To comprehensively review the application of VR and AI technologies in dentistry training, focusing on their impact on cognitive load management and skill enhancement. This study systematically summarizes the existing literature by means of a scoping review to explore the effects of the application of these technologies and to explore future directions.
Geroscience
September 2025
Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam, Gustav Mahlerlaan, 3004, 1081 LA, Amsterdam, the Netherlands.
The increasing prevalence of overweight/obesity among the elderly has significant implications for oral health due to shared pathophysiological mechanisms. Despite its importance, comprehensive reviews on this topic remain limited. This study investigates the association between overweight/obesity and oral health outcomes in adults aged 55 and older.
View Article and Find Full Text PDFEur Geriatr Med
September 2025
Department of Social Science, Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Purpose: To investigate the longitudinal association between chronic pain and decline in activity of daily living (ADL) among community-dwelling older adults aged ≥ 60 years.
Methods: In this systematic review of prospective longitudinal studies with narrative synthesis, a comprehensive literature search was conducted using PubMed and Embase using free-text words and MeSH terms on February 3, 2025. Longitudinal studies that quantitatively assessed ADL at two or more time points and pain at least once were included.