Focused communication Three-dimensional volume estimates of pancreatic fluid collections in relation to clinical outcomes of endoscopic ultrasound-guided treatment.

Background And Aims: The 3-D volume of a pancreatic fluid collection (PFC) has not been fully investigated in endoscopic ultrasound (EUS)-guided treatment.

Methods: In 372 patients, we examined the 3-D volume in relation to the clinical outcomes.

Results: In walled-off necrosis, 3-D volume was associated with time to clinical success and in-hospital mortality with a multivariable subdistribution hazard ratio of 0.43 (95% confidence interval [CI], 0.28-0.66; P = .010) and a multivariable odds ratio of 30.9 (95% CI, 4.31-222; P = .004), respectively (for ≥ 1,000 cm vs. < 250 cm). In pseudocysts, 3-D volume was associated with in-hospital mortality (P = .014) with a multivariable odds ratio of 12.5 (95% CI, 0.81-193; for ≥ 500 cm vs. < 100 cm). The maximum diameter represented a comparable model goodness-of-fit.

Conclusions: PFC volume was associated with the outcomes of EUS-guided interventions, and the maximum diameter may be a reasonable surrogate.