Analyzing clinical laboratory data outcomes in retrospective cohort studies using TriNetX.

Biochem Med (Zagreb)

Department of Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.

Published: October 2025


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Article Abstract

TriNetX, a rapidly growing global network of anonymized patient data, enables clinical researchers to perform large-scale retrospective cohort studies. However, its functionality for querying laboratory data outcomes is significantly constrained, as it only provides the results of the most recent test within a specified observation period. Consequently, the platform is not optimized for analyzing laboratory data collected at multiple time points during an observation period. This paper introduces innovative, data-informed solutions to address these limitations, offering practical guidance for researchers aiming to leverage TriNetX for examining clinical laboratory data.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334939PMC
http://dx.doi.org/10.11613/BM.2025.030502DOI Listing

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