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http://dx.doi.org/10.1016/j.jogc.2025.103067 | DOI Listing |
Orv Hetil
September 2025
2 Szemészeti Klinika, Stadtspital Zürich Birmensdorferstrasse 497, CH-8063 Zürich Schweiz.
JAMA Netw Open
September 2025
Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.
Importance: Patients with advanced cancer frequently receive broad-spectrum antibiotics, but changing use patterns across the end-of-life trajectory remain poorly understood.
Objective: To describe the patterns of broad-spectrum antibiotic use across defined end-of-life intervals in patients with advanced cancer.
Design, Setting, And Participants: This nationwide, population-based, retrospective cohort study used data from the South Korean National Health Insurance Service database to examine broad-spectrum antibiotic use among patients with advanced cancer who died between July 1, 2002, and December 31, 2021.
Cell Biochem Biophys
September 2025
Medical Biotechnology Research Center, School of Paramedical Sciences, Guilan University of Medical Sciences, Rasht, Iran.
In cardiovascular research, melatonin has shown promise in exhibiting antifibrotic properties and modulating endoplasmic reticulum (ER) stress. However, the exact mechanism by which it influences myocardial fibrosis has not been fully clarified. Therefore, this research aimed to investigate the inhibitory effect of melatonin on the progression of myocardial fibrosis through a mechanism involving the BIP/PERK/CHOP signaling pathway, both in silico and in vivo experimental models.
View Article and Find Full Text PDFAnn Biomed Eng
September 2025
Department of Midwifery, Faculty of Health Sciences, Sakarya University, 54100, Sakarya, Turkey.
The incorporation of AI-supported language models into the healthcare sector holds significant potential to revolutionize nursing education, research, and clinical practice. Within this framework, ChatGPT has emerged as a valuable tool for personalizing educational materials, enhancing academic productivity, expediting clinical decision-making processes, and optimizing research efficiency. In the realm of nursing education, ChatGPT offers numerous advantages, including the preparation of course content, facilitation of student assessments, and the development of simulation-based learning environments.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of Research and Innovation, Medway NHS Foundation Trust, Gillingham, ME7 5NY, UK.
Robotic surgery has transformed the field of surgery, offering enhanced precision, minimal invasiveness, and improved patient outcomes. This narrative review explores the multifaceted aspects of robotic surgery, examining the challenges, recent advances, and future prospects for its integration into healthcare. Our comprehensive analysis of 48 studies reveals significant geographic disparities in robotic surgery research and implementation, with 68.
View Article and Find Full Text PDF