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Purpose: To identify clinical and surgical risk factors associated with recurrent rhegmatogenous retinal detachment (RRD) in the index eye and RRD in the fellow eye.
Methods: Retrospective observational study of adult patients who underwent RRD repair at two tertiary care centers over six years.
Results: Among 794 primary RRD patients, recurrence occurred in 20.5%, and RRD in the fellow eye was observed in 5.2%. Postoperative visual acuity significantly improved at one year (95% CI -0.44-0.30; P < 0.001). Higher recurrence rates were found in patients with prolonged symptom duration (P = 0.005), preoperative proliferative vitreoretinopathy (P = 0.006), and worse initial visual acuity (P < 0.001). Recurrences were most frequent within the first 90 days postoperatively, while fellow eye RRD primarily occurred after one year. Pneumatic retinopexy (PnR) (SE 0.37; 95% CI 1.07-4.64, P = 0.03) and the extent of detachment (SE 0.04; 95% CI 1.0-1.2; P = 0.005) were significant predictors of recurrence in multivariate analyses. Age (SE 0.01; 95% CI 1.01-1.05; P = 0.01) and male sex (SE 0.38; 95% CI 1.66-7.47; P = 0.001) were significant predictors for fellow eye RRD.
Conclusion: The study highlights PnR and detachment extent as significant predictors of RRD recurrence. It also identifies older age and male sex as risk factors for RRD in the fellow eye. Our findings emphasize the importance of risk stratification and recommend close monitoring during the first 90 days and beyond the one-year postoperative period.
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http://dx.doi.org/10.1097/IAE.0000000000004641 | DOI Listing |
Transl Vis Sci Technol
September 2025
Department of Ophthalmology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.
Purpose: To evaluate choroidal vasculature using a novel three-dimensional algorithm in fellow eyes of patients with unilateral chronic central serous chorioretinopathy (cCSC).
Methods: Patients with unilateral cCSC were retrospectively included. Automated choroidal segmentation was conducted using a deep-learning ResUNet model.
Oral Oncol
September 2025
Center for Surgery and Public Health, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital; Center for Head and Neck Oncology, D
Introduction: Delays in head and neck cancer (HNC) diagnosis and treatment and financial burdens of care are often rooted in social determinants of health (SDOH), such as financial instability, socioeconomic status (SES), health insurance status, and transportation barriers. While these factors are well recognized, their underlying impact on access to care remains underexplored; this qualitative study aims to investigate how these SDOH facilitate or hinder HNC care through insights from patients and healthcare workers (HCWs) in the United States, to identify targets for intervention.
Methods: Semi-structured interviews were conducted with patients with newly diagnosed HNC, and HCWs caring for these patients, between June 2022 and July 2023.
Transl Vis Sci Technol
September 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Purpose: To investigate the spatial relationship between choroidal vortex veins (VVs), choroidal watershed zones (CWZs), and polypoidal lesion distribution in different subtypes of polypoidal choroidal vasculopathy (PCV) categorized by choroidal vascular hyperpermeability (CVH) status.
Methods: This retrospective study analyzed 58 treatment-naïve PCV eyes using widefield imaging to map dominant VVs, CWZs, and lesion locations. Eyes were stratified into CVH (n = 32) and non-CVH (n = 26) groups.
Invest Ophthalmol Vis Sci
September 2025
Department of Ophthalmology, University of California, Los Angeles, Los Angeles, California, United States.
Purpose: Simulations suggest that displacement of rectus extraocular muscle pulleys in superior oblique (SO) palsy accounts for incomitant strabismus patterns even without postulating SO contractile weakness. We asked how rectus extraocular muscle pulleys reorient during head tilt in SO palsy.
Methods: In 13 subjects with unilateral SO palsy, supine magnetic resonance imaging (MRI) in 2-mm-thick quasi-coronal planes in target-controlled central gaze was repeated in both lateral decubitus positions equivalent to 90° head tilts.
Indian J Ophthalmol
September 2025
Cataract and Glaucoma Services, Sankara Eye Hospital, Sivanandapuram, Coimbatore, Tamil Nadu, India.
Purpose: To compare the optical coherence tomography angiography (OCTA) findings of retinal microvasculature in anisometropic amblyopic eyes with fellow eyes.
Methods: A comparative observational study was conducted in children with unilateral anisometropic amblyopia to compare the OCTA findings of retinal microvasculature between amblyopic and normal fellow eyes. Major outcome measures included superficial vessel density, deep vessel density, and foveal avascular zone (FAZ) parameters (area, perimetry, acircularity index) of amblyopic eye and fellow eye on OCTA.