98%
921
2 minutes
20
The molecular revolution of the 1990s brought insights into the tremendous breadth of ecological and evolutionary diversity harbored within the bacterial and archaeal domains of life, enabling scientists to peer into the proverbial microbial black box. Many of these early molecular efforts focused on microbes in marine surface waters, given their global relevance and ease of extraction from seawater via filtration. From molecular surveys of marine microbial communities, there emerged a limited number of taxa with marked numerical dominance and distribution across ocean realms. One of these lineages is the now well-studied family. Three decades of studying roseobacter members, many of which are amenable to both laboratory culture and genetic manipulation, have led to discoveries in how microbial heterotrophs process diverse marine organic matter, drive biogeochemical cycles, and interact with primary producers.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1146/annurev-marine-050823-105708 | DOI Listing |
Probiotics Antimicrob Proteins
September 2025
School of Life Science, Liaoning Normal University, Dalian, 116081, China.
Cutibacterium acnes (C. acnes, formerly classified as Propionibacterium acnes) is a Gram-positive bacterium that contributes to the development of acne vulgaris, resulting in inflammation and pustule formation on the skin. In this study, we developed and synthesized a series of antimicrobial peptides (AMPs) that are derived from the skin secretion of Rana chensinensis.
View Article and Find Full Text PDFJ Agric Food Chem
September 2025
State Key Laboratory of Green Pesticide, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Structurally unique halichonine B is promising for the design of pharmaceutical leads, while function-oriented optimization is unknown in agrochemical science. Our recent practical synthesis offers a great chance for the discovery of antimicrobial leads. "Linker plus replaceable substituents" is exerted, in which up to 9 unique linkers together with diverse substituents from a wide chemical space are investigated for optimization of the readily available drimanyl amine.
View Article and Find Full Text PDFPLoS Pathog
September 2025
Department of Molecular, Cellular and Developmental Biology, University of California, Santa Cruz, California, United States of America.
The discovery of the endosymbiotic bacteria Wolbachia as an obligate symbiont of. filarial nematodes has led to antibiotic-based treatments for filarial diseases. While lab.
View Article and Find Full Text PDFFront Microbiol
August 2025
State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Introduction: Manganese-oxidizing bacteria (MOB) play a critical role in converting soluble Mn(II) to insoluble Mn(III/IV) oxides, which have been widely applied for environmental remediation, particularly in heavy metal pollution control. Therefore, the discovery of novel MOB strains is of great significance for advancing pollution mitigation and ecosystem restoration.
Methods: In this study, a manganese-oxidizing bacterial strain was isolated from Mn-contaminated soil near an electroplating factory using selective LB medium supplemented with 10 mmol/L manganese chloride (MnCl), and the Leucoberbelin Blue (LBB) assay was employed to screen and identify strains with strong Mn(II)-oxidation ability.
Front Microbiol
August 2025
BIOASTER, Lyon, France.
We propose an innovative technology to classify the Mechanism of Action (MoA) of antimicrobials and predict their novelty, called HoloMoA. Our rapid, robust, affordable and versatile tool is based on the combination of time-lapse Digital Inline Holographic Microscopy (DIHM) and Deep Learning (DL). In combination with hologram reconstruction.
View Article and Find Full Text PDF