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Introduction: This study aimed to determine which strategies most effectively reduce aerosolized particles when removing orthodontic composite attachments.
Methods: A network of AeroSpec portable particle monitors was employed to record particulate data in real-time. Sixteen sensors were placed in a 3-dimensional grid system around an operatory at the University of Washington Orthodontics Department. Composite attachments (Transbond LR; 3M, St Paul, Minn) were removed from the anterior 6 teeth of maxillary and mandibular resin models. Particulate matter of optical diameter ≤2.5 μm (PM) was measured. Three different high-speed handpieces were tested: conventional air-driven (StarDental; DentalEZ, Malvern, Pa), electric (BienAir, Bienne, Switzerland), and air-free (Medidenta, Las Vegas, Nev). Four different suction conditions were tested with each handpiece: none, high-speed intraoral suction (IOS), extraoral suction (EOS), and both together. Four repetitions with each variant were performed. Linear regression was used to compare average and maximum particle concentration by suction and handpiece.
Results: The highest concentration of particles was observed around the operator and decreased farther from the source of composite removal. Linear regression for the main effect of handpiece type indicated lower PM when electric or air-free handpieces were used compared with the conventional handpieces. Linear regression for the main effect of suction showed significant reductions when any suction was used compared with none. The simultaneous use of both IOS and EOS resulted in the greatest reduction in PM.
Conclusions: Using an air-free or electric handpiece, along with simultaneous use of IOS and EOS, reduced the mean particle concentrations by 87% and 86% and the maximum particle concentrations by 92% and 94% near the operator, compared with a conventional handpiece and no suction.
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http://dx.doi.org/10.1016/j.ajodo.2025.05.007 | DOI Listing |
Thromb Res
September 2025
Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany. Electronic address:
Warfarin is a widely used vitamin K antagonist (VKA) with known pleiotropic effects beyond anticoagulation. Preclinical and case-control evidence suggests that warfarin may affect hematopoiesis, but longitudinal human evidence is lacking. To explore this potential effect, we conducted a post-hoc analysis of participants in the Hokusai-VTE and ENGAGE AF-TIMI 48 trials, which randomized patients to warfarin or the direct oral anticoagulant edoxaban with routine laboratory testing at predefined follow-up visits.
View Article and Find Full Text PDFCrit Care Explor
September 2025
Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Professions, Gainesville, FL.
Objectives Background: Monocyte anisocytosis (monocyte distribution width [MDW]) has been previously validated to predict sepsis and outcome in patients presenting in the emergency department and mixed-population ICUs. Determining sepsis in a critically ill surgical/trauma population is often difficult due to concomitant inflammation and stress. We examined whether MDW could identify sepsis among patients admitted to a surgical/trauma ICU and predict clinical outcome.
View Article and Find Full Text PDFClin Transplant
September 2025
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Background: Liver transplantation is the definitive treatment for end-stage liver disease and some cancers. The use of livers from donors following pre-donation cardiac arrest (PDCA), especially with prolonged downtime duration, has been limited outside of the US due to fears over inferior outcomes from ischemic injury. However, PDCA may induce ischemic preconditioning, paradoxically improving post-transplant outcomes.
View Article and Find Full Text PDFPLoS One
September 2025
Faculdade de Psicologia, Universidade de Lisboa, Lisboa, Portugal.
Background: Self-leadership has been associated with several positive organizational outcomes (e.g., performance and innovation).
View Article and Find Full Text PDFPLoS One
September 2025
The George Institute for Global Health, Imperial College London, London, United Kingdom.
Background: Tobacco use remains a major public health challenge in sub-Saharan Africa, with significant gendered dimensions. Place of residence is an important determinant, as rural and urban contexts shape exposure, access, and consumption patterns. This study investigates rural-urban disparities in tobacco use among women in sub-Saharan Africa, with a focus on quantifying the relative contributions of socioeconomic factors.
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