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Neuromorphic photonic computing based on spiking dynamics holds significant promise for next-generation AI accelerators, enabling high-speed, low-latency, and low-energy computing. However, the architecture of neuromorphic photonic systems is severely constrained by large-scale discrete devices. In this work, we propose a photonic spiking neural network (PSNN) architecture utilizing a directly modulated laser and a distributed feedback laser with a saturable absorber (DML-DFB-SA). The distributed feedback laser with a saturable absorber (DFB-SA) functions as a photonic spiking neuron, exhibiting nonlinear neuron-like dynamics. Specifically, we replace the conventional optical source and external modulator with a single directly modulated laser (DML), which simultaneously serves as the optical carrier and performs electro-optic conversion. This integration results in enhanced system compactness and reduced power consumption. Experimental results show that the energy efficiency of the DML-DFB-SA system reaches 0.625 pJ/MAC, representing a significant improvement in energy efficiency. Besides, since both DML and DFB-SA laser chips can be fabricated on an Indium Phosphide (InP) substrate, large-scale integration of photonic spiking neural networks (PSNNs) becomes practical. Moreover, the DML-DFB-SA system exhibits consistent robustness against the chirp effect of DML in short-distance transmissions, which makes it a promising candidate for PSNN applications. To validate the DML-DFB-SA's operational principle, we utilize a time-multiplexed spike coding scheme, enabling a single neuron to emulate the functionality of ten neurons. Experimental evaluations demonstrate a recognition accuracy of 94% on the MNIST dataset. The proposed system and approach provide a promising framework for developing low-energy, large-scale integrated PSNN chips.
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http://dx.doi.org/10.1364/OE.559380 | DOI Listing |
Sci Rep
August 2025
Institute of Physical Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany.
Here we report a novel platform for the detection of nucleocapsid (N) and receptor-binding domain (RBD) of spike (S) proteins of SARS-CoV-2 viruses using the surface plasmon resonance (SPR) technique. We demonstrate that the functionalization of SPR sensors with molecular 2D materials - 1 nm thick carbon nanomembranes (CNMs) significantly enhances sensitivity. CNMs terminated with azide linker (N-CNM) enable covalent bonding of SARS-CoV-2 antibodies for specific immobilization of the N- and S-proteins to the sensor surface.
View Article and Find Full Text PDFCurr Biol
August 2025
Department of Neurobiology, Duke University, Durham, NC 27710, USA. Electronic address:
The cerebellum plays a key role in motor coordination and learning. In contrast to classical supervised learning models, recent work has revealed that climbing fibers (CFs) can signal reward-predictive information in some behaviors. This raises the question of whether CFs may also operate according to the principles of reinforcement learning.
View Article and Find Full Text PDFClin Neurol Neurosurg
October 2025
Department of Neurology, Junwakai Memorial Hospital, Miyazaki, Japan. Electronic address:
This study discusses the first electroencephalography (EEG) findings in two patients with sporadic Creutzfeldt-Jakob disease (sCJD) using magnetoencephalography (MEG). Case 1 involved a 71-year-old male who presented with progressive clumsiness of the right hand. An EEG performed 3 weeks after symptom onset revealed small periodic spikes over the left centroparietal region.
View Article and Find Full Text PDFACS Appl Mater Interfaces
August 2025
Department of Materials Science and Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
Inspired by the human visual system, photonic synapses with photonic sensing and data memorization offer a promising alternative to traditional von Neumann architectures for neuromorphic computing. This study introduces a multifunctional artificial photonic synapse based on solution-processed PEASnI 2D Ruddlesden-Popper perovskite. By modulation of the applied bias voltage, the PEASnI device can switch between two distinct optoelectronic modes.
View Article and Find Full Text PDFCell Rep
August 2025
Department of Neurobiology, Northwestern University, Evanston, IL 60091, USA. Electronic address:
Testing whether the synchrony of action potential firing is a cerebellar coding mechanism requires simultaneous recording, with high temporal fidelity, from populations of identified neurons. Here, we used targeted one-photon voltage imaging at 2-4 kHz to record action potentials from groups of ∼10-300 molecular layer interneurons (MLIs) expressing a positively tuned, genetically encoded voltage indicator, FORCE1f or pAce. In awake resting mice, crus I MLIs fired brief (∼1-ms) spikes at 20-60 spikes/s.
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