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Fiber-based ultrafast laser sources are rapidly expanding in both scientific and industrial domains, making them highly desirable for a variety of applications. The recently demonstrated gain-managed nonlinear (GMN) regime is particularly appealing because it enables the generation of high-energy, clean sub-50-fs pulses in a straightforward setup. However, the complex interaction between nonlinear pulse evolution and the longitudinally evolving gain shaping presents a scientific challenge in understanding how the parameters of GMN laser systems influence the characteristics of the output pulses. In this work, we introduce a computationally efficient approach using the generalized Method of Moments to analyze the dynamically evolving pulse characteristics. This method considers pulse asymmetry in GMN systems and assesses position- and frequency-dependent gain by solving population inversion rate equations. We apply our approach to demonstrate an effective multidimensional parameter optimization of a GMN amplifier.
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http://dx.doi.org/10.1364/OE.549410 | DOI Listing |
Sud Med Ekspert
January 2025
Samara State Medical University, Samara, Russia.
Objective: To develop and implement a method for determining the postmortem interval and the marginal errors of its estimates under conditions of linearly varying external temperature in the format of an online application.
Material And Methods: A computer-assissted numerical search for the absolute minimum point of the objective function obtained from a system of nonlinear equations reflecting the results of double rectal or cranioencephalic thermometry of a corpse under conditions of linearly varying external temperature was carried out. The search algorithm was generalized to possible marginal errors in measuring the initial indicators of temperature and time.
Org Lett
September 2025
Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405-7102, United States.
This communication describes a straightforward method for the trifluoromethylborylation of unactivated alkenes. The reaction proceeds through the formation of an electron donor-acceptor (EDA) complex between a trifluoromethylthiophenium salt and bis(catechol)diboron under broad-spectrum white-light irradiation. Due to the mild reaction conditions, the trifluoromethylborylation tolerates a wide range of functional groups, including esters, acids, alcohols, epoxides, and a variety of heterocycles.
View Article and Find Full Text PDFJ Med Internet Res
September 2025
School of Pharmacy, Sungkyunkwan University, Gyeonggi-do, Republic of Korea.
Background: Owing to the unique characteristics of digital health interventions (DHIs), a tailored approach to economic evaluation is needed-one that is distinct from that used for pharmacotherapy. However, the absence of clear guidelines in this area is a substantial gap in the evaluation framework.
Objective: This study aims to systematically review and compare the economic evaluation literature on DHIs and pharmacotherapy for the treatment of depression.
J Med Internet Res
September 2025
School of Nursing, University of Minho, Braga, Portugal.
Background: The spread of misinformation on social media poses significant risks to public health and individual decision-making. Despite growing recognition of these threats, instruments that assess resilience to misinformation on social media, particularly among families who are central to making decisions on behalf of children, remain scarce.
Objective: This study aimed to develop and evaluate the psychometric properties of a novel instrument that measures resilience to misinformation in the context of social media among parents of school-age children.
Clin Orthop Relat Res
September 2025
Leni & Peter W. May Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Background: Peripheral nerve injury commonly results in pain and long-term disability for patients. Recovery after in-continuity stretch or crush injury remains inherently unpredictable. However, surgical intervention yields the most favorable outcomes when performed shortly after injury.
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