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Article Abstract
In this breastmilk pharmacokinetic study of women undergoing hepatitis C virus treatment with sofosbuvir/velpatasvir, sofosbuvir, GS-331007 (sofosbuvir metabolite), and velpatasvir concentrations in breast milk were 13%, 1.2%, and 41% of maternal plasma concentrations, respectively. The estimated infant daily dose from breastmilk was <1% of the weight-adjusted dose for children.
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