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The current study aimed to explore the efficacy and safety of excisional goniotomy using the Kahook Dual Blade (KDB-GTE) in refractory glaucoma. A total of 20 eyes from 19 subjects with mild to late-stage refractory glaucoma who underwent standalone KDB goniotomyor combined phacoemulsification plusintraocular lens (IOL) implantation (partially combined withgoniosynechialysis) in Beijing Tongren Hospital from August 2021 to April 2023 were included. There were 9 males and 10 females, with a mean age of (57±17) years and a follow-up time of (19.8±6.4) months.The preoperative intraocular pressure (IOP) decreased from (29.4±11.8) mmHg (1 mmHg=0.133 kPa) to (15.7±2.6) mmHg (<0.001). The types of preoperativeanti-glaucoma medications were reduced from 4 (3, 4) to 2 (1, 3) (<0.001). At 12-month follow-up, 70% (14/20) achieved a IOP of≤18 mmHg after medication. No severe complications were reported. This study suggests that KDB-GTE is an effective and minimally invasive surgery for refractory glaucoma, demonstrating significant reductions in both IOP and medication burden, with a favorable safety profile.
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http://dx.doi.org/10.3760/cma.j.cn112137-20241210-02793 | DOI Listing |
Zhonghua Yi Xue Za Zhi
August 2025
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
The current study aimed to explore the efficacy and safety of excisional goniotomy using the Kahook Dual Blade (KDB-GTE) in refractory glaucoma. A total of 20 eyes from 19 subjects with mild to late-stage refractory glaucoma who underwent standalone KDB goniotomyor combined phacoemulsification plusintraocular lens (IOL) implantation (partially combined withgoniosynechialysis) in Beijing Tongren Hospital from August 2021 to April 2023 were included. There were 9 males and 10 females, with a mean age of (57±17) years and a follow-up time of (19.
View Article and Find Full Text PDFJ Glaucoma
July 2025
Department of Ophthalmology, University of Colorado School of Medicine, Denver, CO.
Precis: Combination MIGS procedures are a potentially more efficacious method to decrease mean IOP and glaucoma medication burden; however, our findings question whether the addition of ECP to excisional goniotomy provides significant additional benefit.
Purpose: Combined microinvasive glaucoma surgery (MIGS) procedures are gaining popularity. While the individual efficacy of excisional goniotomy and endoscopic cyclophotocoagulation (ECP) is well established, data supporting their use in combination is lacking.
Indian J Ophthalmol
March 2025
Department of Glaucoma, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Background: The bent ab-interno needle goniectomy (BANG) represents a low-cost indigenous modification designed for ab-interno excisional goniectomy. This technique employs a reverse cystitome (24 G needle) and yields outcomes equivalent to those achieved with the Kahook Dual Blade goniectomy. However, reflux bleeding from Schlemm's canal, with or without anterior chamber shallowing, often impedes angle visualization, thereby limiting the desired treatment extent.
View Article and Find Full Text PDFSemin Ophthalmol
July 2025
Glaucoma Service, LV Prasad Eye Institute, Hyderabad, India.
Purpose: To discuss comprehensively the varied complications after stent-less incisional or excisional minimally invasive glaucoma surgery (MIGS).
Method: A review of reported complications after stent-less MIGS procedures including gonioscopy-assisted transluminal trabeculotomy (GATT), bent needle goniectomy (BANG), Kahook-dual blade goniotomy, and microincisional trabeculectomy (MIT) published between 2014-2024, were analyzed and summarized.
Results: Apart from hyphema, peripheral anterior synechiae, and intraocular pressure spikes, other vision-threatening complications like cyclodialysis, Descemet's detachment, corneal edema, iridodilalysis, vitreous loss or vitreous hemorrhage can also occur intra- or postoperatively after any incisional or excisional MIGS procedures.
BMJ Case Rep
November 2024
Glaucoma, Choithram Netralaya, Indore, Madhya Pradesh, India.