[Myoadaptive overload syndromes of lower extremities in multiple sclerosis patients].

Zh Nevrol Psikhiatr Im S S Korsakova

Kazan State Medical Academy - branch of the Russian Medical Academy of Continuing Professional Education, Kazan, Russia.

Published: August 2025


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Article Abstract

The article addresses the actual problem of chronic pain in patients with multiple sclerosis (MS). Particular attention is paid to the nociceptive component of pain caused by the biomechanics disorders of the spine and the development of myoadaptive overload syndromes (MOSs). A pathogenetic analysis of postural and vicarious mechanisms of musculoskeletal overload occurring due to paresis, spastic hypertonicity, and spinal deformity is presented. Their importance in the pain chronification, decreased motor activity, and the quality of life of MS patients has been reported. The need for an integrative approach to diagnosing and treating pain, including pharmacological methods and correction of biomechanical disorders using soft manual techniques and motor therapy, is substantiated.

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http://dx.doi.org/10.17116/jnevro202512507289DOI Listing

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