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The Baeyer-Villiger Oxidation of Cubyl Ketones: A Synthetic Route to Functionalized Cubanols. | LitMetric

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Article Abstract

The synthesis of functionalized cubanols has been developed via a 2-step protocol comprising of a Baeyer-Villiger oxidation of cubyl ketones, followed by acid hydrolysis. As part of this study, we determine the relative migratory aptitude of cubyl groups in the Baeyer-Villiger oxidation and rationalize these experimental findings with computational studies.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379164PMC
http://dx.doi.org/10.1021/acs.orglett.5c02760DOI Listing

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