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With a fair percentage of all medical care deemed unnecessary for diagnosis and treatment, it is paramount that clinicians consider the rationale for each order and whether it is truly warranted. We present the case of a 71-year-old male with a history of Roux-en-Y gastric bypass who presented with choledocholithiasis and was found to have an incidental finding of a persistently narrowed segment of the right bile duct. With the usage of multiple imaging modalities, particularly CT angiography and intravascular ultrasound via an endobiliary route during biliary drain management, it was confirmed that the narrowing of concern was caused by a benign vascular compression by the right hepatic artery as opposed to a malignancy. This case demonstrates how minimally invasive imaging can reduce further potentially unnecessary tests, and thus costs, for patients.
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http://dx.doi.org/10.7759/cureus.87158 | DOI Listing |
J Eat Disord
September 2025
Center for Nutrition and Therapy (NuT), University of Applied Sciences Muenster, Corrensstraße 25, 48149, Muenster, Germany.
Eating disorders are primarily associated with women and an obsession with thinness. Recent research and social media content show that men are also concerned about their body image, striving for a muscular and athletic physique. To investigate eating disorder tendencies among male content creators with a mesomorphic body type (N = 26), a social media analysis was conducted on Instagram and TikTok over four weeks.
View Article and Find Full Text PDFNat Aging
September 2025
Aging Biomarker Consortium (ABC), Beijing, China.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA.
Dysregulated dopaminergic signaling has been implicated in the pathophysiology of major depressive disorder (MDD) and childhood sexual abuse (CSA), but inconsistencies abound. In a multimodal PET-functional MRI study, harnessing the highly selective tracer [C]altropane, we investigated dopamine transporter availability (DAT) and resting-state functional connectivity (rsFC) within reward-related regions among 112 unmedicated individuals (MDD: n = 37, MDD/CSA: n = 18; CSA no MDD: n = 14; controls: n = 43). Striatal DAT and seed-based rsFC were assessed in the dorsal and ventral striatum and the ventral tegmental area.
View Article and Find Full Text PDFNat Commun
September 2025
Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, 90033, California, USA.
Acad Radiol
September 2025
Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan (J.Y.H., C.L.K., K.L.C.); College of Medicine, National Taiwan University, Taipei, Taiwan (J.Y.H., C.K.H., K.L.C., Y.W.W.); Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan (C.K
Rationale And Objectives: The prognostic implications of myocardial perfusion imaging (MPI) are imperative to provide proper management of coronary artery disease (CAD). This study aimed to quantify the long-term prognostic value of MPI under routine clinical conditions.
Materials And Methods: This single-center retrospective cohort study evaluated all-cause mortality and cause-specific survival according to MPI findings in patients with suspected or known CAD who underwent diagnostic evaluation or assessment of myocardial ischemia and viability in a tertiary referral cardiovascular center.