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Objective: To enhance social connections using artificial intelligence and explore the alleviating effect of emotionally intelligent chatbots on loneliness.
Method: A stratified sampling method was used to distribute the Emotional Social Loneliness Inventory (ESLI) to full-time college students. Based on the ESLI assessment results, 120 young people with severe loneliness were selected as the research subjects. Regularly interact with Replika chatbot to obtain psychological support and academic assistance (continuous intervention for 1 month). Compare the scores of the ESLI scale, SASS CS scale, IES scale, and CD-RISC scale in young individuals with severe loneliness before and 1, 3, and 5 months after intervention.
Results: There was no statistically significant difference in ESLI scores between the two groups of college students before intervention (P>0.05). After 1, 3, and 5 months of intervention, the ESLI scores of the experimental group were lower than those of the control group (P<0.05). There was no statistically significant difference in social anxiety scores between the two groups of college students before intervention (P>0.05). After 1, 3, and 5 months of intervention, the social anxiety scores of the experimental group were lower than those of the control group (P<0.05). There was no statistically significant difference in social self-efficacy and psychological resilience levels between the two groups of college students before intervention (P>0.05). After intervention, the social self-efficacy and CD-RISC scores of the experimental group were higher than those of the control group (P<0.05).
Conclusion: High emotional intelligence AI chatbots can significantly improve and alleviate feelings of loneliness and enhance social skills, opening up new avenues for technology assisted psychological intervention.
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http://dx.doi.org/10.1080/17483107.2025.2540494 | DOI Listing |
Tissue Eng Regen Med
September 2025
Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #505 BanPo-Dong, SeoCho-Gu, Seoul, 06591, Republic of Korea.
Background: Sjögren's syndrome (SS) is a chronic autoimmune disease delineated by excessive lymphocyte infiltration to the lacrimal or salivary glands, leading to dry eye and dry mouth. Exosomes secreted from mesenchymal stem cells (MSC) are known to have anti-inflammatory and tissue regeneration abilities. This study endeavored to demonstrate the effect of MSC-derived exosomes on the clinical parameter of dry eyes and associated pathology in SS mouse model.
View Article and Find Full Text PDFJMIR Public Health Surveill
August 2025
College of Design and Engineering, National University of Singapore, Singapore, Singapore.
Background: The COVID-19 lockdowns led to significant resource constraints, potentially impacting mental health and decision-making behaviors. Understanding the psychological and behavioral consequences could inform designing interventions to mitigate the negative impacts of episodic scarcity during crises like pandemics.
Objective: To investigate the effects of perceived scarcity on mental health (stress and fear), cognitive functioning, time and risk preferences (present bias and risk aversion), and trade-offs between groceries, health, and temptation goods during and after the COVID-19 lockdown in Shanghai.
J Food Sci
September 2025
Faculty of Computing, Federal University of Uberlandia, Uberlândia, Brazil.
The coffee roasting process is a critical factor in determining the final quality of the beverage, influencing its flavour, aroma, and acidity. Traditionally, roast-level classification has relied on manual inspection, which is time-consuming, subjective, and prone to inconsistencies. However, advancements in machine learning (ML) and computer vision, particularly convolutional neural networks (CNNs), have shown great promise in automating and improving the accuracy of this process.
View Article and Find Full Text PDFMov Disord Clin Pract
September 2025
Neurology Unit, Neuromotor and Rehabilitation Department, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Background: GBA1 variants are the major genetic risk factor for Parkinson's Disease (PD) and account for 5-30% of PD cases depending on the population and age at onset of the disease.
Objectives: The aim of this study was to assess whether Artificial Intelligence (AI) could predict GBA1-mutated genotype in PD (GBA1-PD). Particularly, the main objective was to identify a Machine Learning (ML) model capable of accurately providing a pre-test estimate of GBA1-mutated status, relying on the clinical and demographic variables with the highest predictive value.
Medicine (Baltimore)
September 2025
Department of Spinal Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Functional constipation (FC) is a prevalent gastrointestinal disorder that can significantly impact patients' quality of life. In this study, we aimed to evaluate the effectiveness and safety of "abdominal tuina" and oral mosapride citrate tablets in the treatment of FC. Ninety patients with FC were randomly assigned to receive either "abdominal tuina" treatment or oral mosapride citrate tablets.
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