Penile Metastasis from Prostate Cancer: Detection on F-PSMA-1007 PET/CT.

Mol Imaging Radionucl Ther

Cobalt Medical Charity, Cheltenham, UK.

Published: August 2025


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Article Abstract

A 74-year-old man with a history of prostate cancer and rising prostate-specific antigen underwent F-prostate specific membrane antigen PSMA)-1007 positron emission tomography/computed tomography for investigation of oligometastatic disease. There was evidence of PSMA avid local recurrence findings with pelvic and retroperitoneal nodal metastases and skeletal deposits. Although rare and could easily be mistaken for contamination, a small penile metastasis was found. This is associated with poor prognosis and could impact further management. This case highlights the importance of a detailed review of the penis, to ensure differentiation between urinary activity and pathological uptake.

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http://dx.doi.org/10.4274/mirt.galenos.2025.32815DOI Listing

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