Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: The ENDORISK model estimates the risk of lymph node metastases (LNM) in endometrial carcinoma (EC) patients using preoperative clinical variables and biomarkers. This qualitative study investigated healthcare providers' (HCP) perspectives on the use of the model and barriers and facilitators for clinical implementation.

Methods: Eight focus group interviews were performed among HCPs. A semi-structured interview guide was used based on the Grol and Wensing implementation model.

Results: Focus groups included gynecologists, residents of gynecology, pathologists, radiation oncologists, and a nurse specialist (n = 41). ENDORISK was deemed supportive for counseling of patients and shared decision-making for optimal surgical and adjuvant treatment. Barriers for implementation were difficulty in explaining the model and risk percentages to patients, differences in preoperative diagnostic tools used per hospital, and use of the model with the sentinel node procedure. Facilitators were a clear guideline for using the model with a predefined risk cutoff and making the model easily understandable for patients. A 10% risk cutoff was considered clinically relevant for lymph node assessment.

Conclusion: HCP found ENDORISK use in clinical practice supportive for patient counseling. Future implementation should focus on a user-friendly interface, a cohesive guideline, and training to aid efficient use and counseling of patients.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314653PMC
http://dx.doi.org/10.1002/cam4.71103DOI Listing

Publication Analysis

Top Keywords

lymph node
12
endometrial carcinoma
8
healthcare providers'
8
barriers facilitators
8
counseling patients
8
risk cutoff
8
model
7
risk
5
patients
5
implementation
4

Similar Publications

Cystic lesions of the head and neck encompass a wide spectrum of benign and malignant entities, which often presents diagnostic challenges as a result of the region's complex anatomy. Despite extensive literature, variability persists in diagnostic strategies and approaches. Fine-needle aspiration biopsy is a commonly used and highly effective method for the initial assessment of these lesions by offering a minimally invasive technique to collect cellular material for diagnostic evaluation.

View Article and Find Full Text PDF

Background: T follicular helper (TFH) cell lymphoma is complex, and we hope to provide a new perspective for its diagnosis.

Methods: We analysed the immunophenotypes of 89 mature T-cell lymphomas, including 52 nodal lymphomas of TFH origin, as well as 32 benign lymph node samples and 30 healthy bone marrow samples, by flow cytometry (FCM).

Results: Among pan-T cell markers, CD4CD5CD3 is the typical pattern that distinguishes TFH lymphoma from other T-cell lymphomas.

View Article and Find Full Text PDF

Impact of lymph node dissection on survival after neoadjuvant immunochemotherapy for esophageal squamous cell cancer: a double-center real-world retrospective study.

Cancer Immunol Immunother

September 2025

Guangdong Provincial Clinical Research Center for Cancer, State Key Laboratory of Oncology in South China, Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangdong Esophageal Cancer Institute, Guangzhou, 510060, China.

Background: Previous studies indicated that over-dissection of lymph nodes might impair the efficacy of immunotherapy. This study aims to explore the prognostic value of ypN + status and the impact of lymph node dissection (LND) on survival after neoadjuvant immunochemotherapy (NICT) for esophageal squamous cell cancer (ESCC).

Methods: This double-center retrospective study enrolled 206 consecutive ESCC patients who underwent NICT followed by esophagectomy between 2018 and 2024.

View Article and Find Full Text PDF

Background: Minimally invasive pancreaticoduodenectomy (MIPD) is used more commonly, but this surge is mostly based on observational data. This meta-analysis aimed to compare the short-term outcomes between MIPD and open pancreaticoduodenectomy (OPD) using data collected from randomized controlled trials (RCTs).

Methods: We searched PubMed, Cochrane Library, Embase, and Web of Science databases for RCTs comparing MIPD and OPD published before December 10, 2024.

View Article and Find Full Text PDF

Gastroenteropancreatic neuroendocrine tumors: A retrospective study conducted in the Colombian Southwest.

Rev Gastroenterol Mex (Engl Ed)

September 2025

Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia; Departamento de Medicina Interna, Servicio de Gastroenterología, Fundación Valle del Lili, Cali, Colombia. Electronic address:

Introduction And Aim: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare neoplasms originating in neuroendocrine cells from the gastric mucosa and submucosa, small intestine, large intestine, rectum, and pancreas. Our aim was to describe their histopathologic, endoscopic, and clinical characteristics and the experience with these tumors at a tertiary care hospital center in the Colombian Southwest.

Materials And Methods: A retrospective, analytic, observational, and descriptive study included 93 patients diagnosed with GEP-NETs, within the time frame of 2018 and 2022.

View Article and Find Full Text PDF