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http://dx.doi.org/10.4103/tjem.tjem_110_25 | DOI Listing |
Ann Med Surg (Lond)
September 2025
Department of Orthopedics, National Trauma Center, Kathmandu, Nepal.
Introduction: Snakebites, recognized as a neglected tropical disease by the WHO, cause significant morbidity and mortality globally. Although antivenom is the primary treatment, managing complications like compartment syndrome (CS) and soft tissue necrosis remains challenging. This case report describes a 39-year-old woman who developed CS following a green pit viper bite and subsequent antivenom administration, necessitating a fasciotomy.
View Article and Find Full Text PDFPLoS Negl Trop Dis
September 2025
Ocean and Fisheries Development International Cooperation Institute, College of Fisheries Science, Pukyong National University, Busan, Republic of Korea.
Background: Climate change is anticipated to significantly impact the biogeographic distribution of snakes, leading to notable shifts in their habitats toward anthropogenic landscapes. This may potentially increase the incidence of Big Four species (Bungarus caeruleus, Daboia russelii, Echis carinatus, and Naja naja) envenomation, a notable human-health risk that has not yet been assessed in India being the most affected country in South Asia. Therefore, this study integrates species distributions with socioeconomic and healthcare data to prioritize areas for targeted interventions to mitigate the envenomation risks effectively in India.
View Article and Find Full Text PDFJ Med Toxicol
September 2025
Department of Emergency Medicine, LSU Health Shreveport, 1501 Kings Highway, PO Box 33932, Shreveport, LA, 71130-3932, USA.
Introduction: Copperheads and cottonmouths are responsible for most snake envenomations in Louisiana. While the United States Food and Drug Administration has approved both Crotalidae polyvalent immune Fab (FabAV) and Crotalidae immune F(ab') (Fab2AV) for Agkistrodon envenomations, data is limited comparing their efficacies for this indication.
Methods: This is a retrospective study comparing FabAV to Fab2AV in the treatment of suspected Agkistrodon envenomations in Louisiana between April 2017 and October 2024.
BMC Pediatr
August 2025
Department of Paediatrics, Gombe State University, Gombe State, Nigeria.
Background: Nigeria remains one of the highest burden bearers of snakebite envenoming in sub-Saharan Africa. In Northeastern Nigeria, where agricultural practice, livestock herding and outdoor play—especially during the dark hours—are common, children are frequently exposed to snakes. Due to the unique challenges posed by paediatric snakebite envenoming and the paucity of data on paediatric snakebites, there is need for local research on this subject.
View Article and Find Full Text PDFPharmaceuticals (Basel)
August 2025
Research Group on Bioactive Substances (GISB), Faculty of Pharmaceutical and Food Sciences, University of Antioquia, Medellin 050010, Colombia.
: Most snakebite incidents in Latin America are caused by species of the genus. Their venom induces severe local effects, against which antivenom therapy has limited efficacy. Metabolites derived from have demonstrated anti-inflammatory and anticoagulant properties, suggesting their potential as therapeutic agents to inhibit the local effects induced by venom.
View Article and Find Full Text PDF