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Multi-omics profiling and molecular pathways in esophageal adenocarcinoma. | LitMetric

Multi-omics profiling and molecular pathways in esophageal adenocarcinoma.

Clin Res Hepatol Gastroenterol

Tianjin NanKai Hospital, Tianjin Medical University, Tianjin 300100, China; Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Tianjin 300100, China; Institute of Integrative Medicine for Acute Abdominal Diseases, Tianjin 300100, China. Electronic address: wyct

Published: July 2025


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Article Abstract

Esophageal adenocarcinoma (EAC) is an aggressive malignancy with a rising incidence and poor prognosis. This review integrates current insights into the molecular features of EAC, focusing on the application of multi-omics approaches to unravel its genetic, transcriptomic, metabolic, and microenvironmental alterations. By identifying key biomarkers and therapeutic targets, we highlight the transformative potential of multi-omics in advancing precision medicine for EAC.

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Source
http://dx.doi.org/10.1016/j.clinre.2025.102653DOI Listing

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