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We report a case of transcatheter paravalvular leak (PVL) closure assisted by three-dimensional (3D) printing and intracardiac echocardiography (ICE) in a patient with complex valvular history. A 70-year-old male manifested acute exacerbation of dyspnea, accompanied by orthopnea and nocturnal paroxysmal respiratory distress. Echocardiographic evaluation revealed severe aortic PVL. After multidisciplinary heart team evaluation, transcatheter aortic PVL closure was selected as the preferred therapeutic strategy. The preoperative assessment of PVL location, size, and morphology using 3D printing technology accurately guided the interventional position and the selection of the occluder size and the successful completion of closed treatment under local anesthesia, which was assisted by intracardiac echocardiography to ensure the safety and smoothness of the procedure.
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http://dx.doi.org/10.1002/ccr3.70640 | DOI Listing |
Regen Biomater
August 2025
Institute of Stomatology & Oral Maxilla Facial Key Laboratory, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Reconstructing bone defects remains a significant challenge in clinical practice, driving the urgent need for advanced artificial grafts that simultaneously promote vascularization and osteogenesis. Addressing the critical trade-off between achieving high porosity/strength and effective bioactivity at safe ion doses, we incorporated strontium (Sr) into β-tricalcium phosphate (β-TCP) scaffolds with a triply periodic minimal surface (TPMS) structure using digital light processing (DLP)-based three-dimensional (3D) printing. Systematically screening Sr concentrations (0-10 mol%), we identified 10 mol% as optimal, leveraging the synergy between the biomimetic TPMS architecture, providing exceptional mechanical strength (up to 1.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
August 2025
Department of Prosthodontics and Crown & Bridge, SRM Dental College, Ramapuram Campus, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India.
Background Of The Study: known for its bioactive phytochemicals and antimicrobial potential; however, studies evaluating its outcome on the color, mechanical properties and antimicrobial activity of 3D-printed provisional dental resins are lacking. So this study evaluate the effect of seed extract incorporation on the color assessment, flexural strength, compressive strength, microhardness and antimicrobial activity of 3D-printed provisional crown and bridge resin.
Materials And Methods: A total of 240 samples were prepared, with 60 samples allocated to four groups based on 0 %, 1.
Environ Sci Pollut Res Int
September 2025
Department of Dyes and Chemical Engineering, Bangladesh University of Textiles, Dhaka, Bangladesh.
This study quantitatively evaluated the adsorption performance of natural bentonite for removing three dye classes-cationic (Basic dye: BEZACRYL RED GRL), anionic (Reactive dye: AVITERA LIGHT RED SE), and non-ionic (Disperse dye: BEMACRON BLUE HP3R) from synthetic textile wastewater. Batch adsorption experiments were conducted under varying conditions of contact time (15-90 min), adsorbent dosage (20-60 g L⁻), pH (4 and 12), and temperature (25-100 °C), with dye concentrations quantified by UV-Vis spectroscopy. At a contact time of 30 min and room temperature (25 °C), maximum removal efficiencies reached 99.
View Article and Find Full Text PDFActa Ortop Mex
September 2025
Servicio de Ortopedia y Traumatología, Hospital de San Rafael, Hospitales Pascual. Cádiz, España.
Introduction: anatomical deformities such as developmental dysplasia of the hip (DDH) and Perthes disease represent a challenge for reconstruction. The use of 3D-printed models can be helpful for assessing the deformity, bone mass, implant size, and orientation.
Objectives: to prospectively evaluate the outcomes of 3D simulation in primary total hip arthroplasty.
Biofabrication
September 2025
Institute of Macromolecular Chemistry, Institute of Macromolecular Chemistry Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Prague, Prague, 162 06, CZECH REPUBLIC.
Extensive peripheral nerve injuries often lead to the loss of neurological function due to slow regeneration and limited recovery over large gaps. Current clinical interventions, such as nerve guidance conduits (NGCs), face challenges in creating biomimetic microenvironments that effectively support nerve repair. The developed GrooveNeuroTube is composed of hyaluronic acid methacrylate and gelatin methacrylate hydrogel, incorporating active agents (growth factors and antibacterial agents) encapsulated within an NGC conduit made of 3D-printed PCL grid fibers.
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