98%
921
2 minutes
20
IntroductionFractures of the tibia and fibula occurring at the same level can be technically challenging. Fibular plating (FP) prior to intramedullary nailing (IMN) may facilitate tibial reduction, stabilization, and subsequent tibial healing. The primary goal of this study was to compare tibial fracture healing between FP and no fibular plating (NFP) in patients with same-level distal third tibia/fibula fractures.MethodsPatients ≥18 years with distal third tibia/fibula fractures occurring at the same level were randomized to FP or NFP prior to infrapatellar IMN. Same-level fractures were defined as distal third tibia fractures with an ipsilateral supra-syndesmotic distal third fibula fracture. Intraoperative parameters, patient-reported outcome measures (PROMs), modified Radiographic Union Scale in Tibial fractures (mRUST) scores, radiographic alignment, and adverse events were recorded.Results30 patients were recruited, with 15 randomized to each group. There were no differences in baseline characteristics between groups. Total operative time was longer in FP compared with NFP (105.5 vs 65.8 minutes, = .001). Mean duration of fibular fixation was 28.1 minutes (SD = 11.9). There was no difference in duration of IMN; however, less time was required to pass the guidewire in FP (4.5 vs 11.8 minutes, = .01). Patients in FP had higher mRUST scores at 6 months, lower incidence of delayed union, and shorter fibular time-to-union. There were no differences in alignment between groups.ConclusionFibula-first fixation facilitated passage of the tibial guidewire and resulted in a modest improvement in the rate of tibia fracture healing. The results of this pilot study suggest that fibula-first fixation may be beneficial in patients with same-level distal third tibia/fibula fractures. Further research with larger sample sizes is needed to determine which patients may benefit most from fibula-first fixation.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/10225536251364177 | DOI Listing |
Eur Heart J Cardiovasc Imaging
September 2025
Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Aims: Fetal circulation undergoes complex changes in congenital heart disease (CHD) that are challenging to assess with fetal echocardiography. This study aimed to assess clinical feasibility and diagnostic value of 4D flow cardiac magnetic resonance (CMR) in fetal CHD.
Methods And Results: Pregnant women in advanced third trimester pregnancy with fetal CHD were prospectively recruited for fetal CMR between 08/2021 and 11/2024.
Future Oncol
September 2025
Medical Oncology Unit, Comprehensive Cancer Centre, AUSL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Background: Esophageal cancer is a rare neoplasm, with more than 0.6 million new cases and 0.54 million deaths worldwide in 2020.
View Article and Find Full Text PDFCureus
August 2025
Diagnostic Radiology, Mardan Medical Complex, Mardan, PAK.
Introduction: Fractures are a common occurrence in childhood, with approximately one-third of boys and girls sustaining at least one fracture before the age of 17. Both-bone forearm fractures, particularly those involving the radius and ulna, are more common in the non-dominant hand and in boys and usually involve the distal portions of both bones. If not properly treated, these injuries can have a significant impact on limb function.
View Article and Find Full Text PDFCureus
August 2025
Department of Oral and Maxillofacial Surgery, Virgen del Rocio University Hospital, School of Medicine, University of Seville, Seville, ESP.
The presence of a fourth supernumerary molar in the mandible represents a rare anomaly of dentofacial development. Here, we describe an exceptional, previously unreported case of a 33-year-old man with a solitary ectopic supernumerary fourth molar located in the sigmoid notch, which was associated with a dentigerous cyst. In addition, a review of the literature related to this uncommon and atypical clinical presentation is provided.
View Article and Find Full Text PDFNeurotherapeutics
September 2025
Department of Neurology, Peking University Third Hospital, Beijing, 100191, China; Beijing Key Laboratory of Biomarker and Translational Research in Neurodegenerative Diseases, Beijing, 100191, China; Key Laboratory for Neuroscience, National Health Commission/Ministry of Education, Peking Universit
Extensive research has confirmed that omega-3 fatty acids provide cardiovascular protection primarily by activating the G protein-coupled receptor 120 (GPR120) signaling pathway. However, natural activators of this receptor often lack sufficient strength and precision. TUG-891, a recently synthesized selective GPR120 activator, has displayed significant therapeutic potential in multiple disease.
View Article and Find Full Text PDF