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COVID-19 infection is associated with stroke due to various proposed mechanisms, including cerebral vasculitis, arterial and venous thrombosis. Vessel wall imaging, although not pathognomonic, interpreted in the appropriate clinical context and supportive laboratory findings, can help clarify the diagnosis and differentiate the etiology from other mechanisms of CNS involvement. We describe a patient with extensive anterior circulation vasculitis and ischemic stroke in the setting of COVID-19, with sparing of the posterior circulation.
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http://dx.doi.org/10.7759/cureus.86818 | DOI Listing |
Cureus
August 2025
Department of Internal Medicine, Local Health Unit of Santa Maria, Lisbon, PRT.
Polyarteritis nodosa (PAN) rarely affects both intracranial and mesenteric arteries. Evidence on optimal timing of revascularisation and the role of interleukin-6 blockade remains limited. A 73-year-old man with longstanding ankylosing spondylitis presented with weight loss and elevated inflammatory markers.
View Article and Find Full Text PDFFront Immunol
September 2025
Department of Rheumatology and Immunology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Background: The coexistence of neuropsychiatric systemic lupus erythematosus (NPSLE) and primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system (CNS) (PCNS DLBCL) is extremely rare in clinical practice. This article retrospectively analyzes the clinical manifestations, imaging examinations, pathological diagnosis, and treatment process of a patient with NPSLE, from the appearance of intracranial abnormal signal shadows to the final diagnosis of PCNS DLBCL.
Case Summary: A 32-year-old Chinese female patient had previously visited our hospital due to vomiting and delirium and was diagnosed with NPSLE.
Stroke
September 2025
Division of Neurointerventional Surgery, Department of Neurosurgery, University of Maryland Medical Center, Baltimore (H.C., D.G.).
Background: Retinal artery occlusion (RAO) is a form of ischemic stroke per the American Heart Association, yet high-level evidence guiding management and prognostication is limited. The risk of future cerebral infarction following nonarteritic isolated RAO (iRAO; without concomitant cerebral infarction) is unclear. This study compares the risk of stroke recurrence following iRAO versus nondisabling ischemic cerebrovascular events (NICEs), including transient ischemic attacks and minor ischemic strokes.
View Article and Find Full Text PDFCase Rep Med
August 2025
Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
A 65-year-old woman presented with pneumococcal sepsis and meningitis. Despite appropriate antimicrobial therapy and intravenous (IV) dexamethasone, her mental status did not improve. Findings of brain imaging were suggestive of cerebral vasculitis.
View Article and Find Full Text PDFMultimed Man Cardiothorac Surg
September 2025
Division of Cardiac Surgery, Department of Surgery, University of Maryland, Baltimore, MD, USA
Concomitant aortic root and pulmonic root aneurysms secondary to giant cell arteritis are extremely rare. We present a case of a patient with giant cell arteritis who underwent concomitant valve-sparing aortic root replacement and valve-sparing pulmonary root replacement along with tricuspid valve repair.
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