Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Immunosuppressive therapies are essential for transplant recipients and are increasingly prescribed in autoimmune and oncologic conditions. In France, community pharmacists are legally involved in Therapeutic Patient Education (TPE) and medication counseling. However, their level of knowledge regarding immunosuppressive therapies remains poorly documented.
Objectives: This study aimed to assess the knowledge of French pharmacy professionals-pharmacists, pharmacy technicians, and pharmacy students-regarding Immunosuppressive therapies, particularly in the context of transplant patient management. It also sought to identify gaps in counseling practices and educational needs.
Methods: A cross-sectional survey was conducted from April 2022 to March 2023 using a 20-item online questionnaire. The survey was distributed nationally to community pharmacy professionals. Questions covered immunosuppressive therapy, patient education, lifestyle risks, and infectious precautions. Responses were weighted based on clinical importance, and group comparisons were performed using non-parametric statistical tests.
Results: A total of 265 participants completed the survey (177 pharmacists, 50 students, 38 technicians). Pharmacists scored significantly higher than technicians (11.76 ± 6.2 vs. 8.00 ± 6.5; p = 0.004). Students showed intermediate scores with greater variability. Major knowledge gaps were observed regarding missed doses, food interactions, rejection signs, and self-medication risks. Only 22.6% identified self-medication as unsafe for transplant patients. Lifestyle and travel counseling practices were inconsistent across groups. TPE training was reported by 51.4% of pharmacists, 28% of students, and 5.3% of technicians.
Conclusion: The study revealed heterogeneous knowledge and counseling practices among pharmacy professionals regarding immunosuppressive therapies. These findings highlight the need for targeted education, integration of immunosuppressive topics into pharmacy curricula, and enhanced collaboration between hospital and community pharmacists to support safe and effective long-term care for immunosuppressed patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.japh.2025.102484 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Balance Between Autoimmunity and Infection: A Case Report of Concomitant Pathology of Pulmonary Nocardia and Granulomatosis with Polyangiitis at Initial Presentation.
Eur J Case Rep Intern Med
August 2025
Medical Subspecialities Department, Rheumatology Section, King Fahad Medical City, Riyadh, Saudi Arabia.
Unlabelled: Concurrent presentation of pulmonary nocardiosis and granulomatosis with polyangiitis (GPA) is exceptionally rare and diagnostically challenging, given the overlapping clinical and radiological features. We report a 54-year-old female with fever, cough, weight loss, and arthralgia. Chest imaging showed multiple pulmonary nodules; serology revealed positive anti-neutrophil cytoplasmic antibodies -proteinase 3, and lung biopsy demonstrated necrotizing granulomatous inflammation with Nocardia species.
View Article and Find Full Text PDFA Silent Invader: Asymptomatic Rhodococcus Infection Unmasked in A Patient with Ectopic ACTH-Dependent Cushing's Syndrome.
Eur J Case Rep Intern Med
August 2025
Charleston Area Medical Center, Charleston, USA.
Introduction: species, particularly , are rare opportunistic pathogens that typically affect immunocompromised individuals. These infections usually present with respiratory or systemic symptoms and are often linked to environmental exposure. Asymptomatic infections are exceedingly rare and pose unique diagnostic and therapeutic challenges.
View Article and Find Full Text PDFRapidly Progressive Primary Central Nervous System Vasculitis: A Rare Case with Multifocal Small and Medium Vessel Involvement.
Eur J Case Rep Intern Med
August 2025
Department of Internal Medicine, Dubai Hospital, Dubai Health, Dubai, Dubai, United Arab Emirates.
Introduction: Primary central nervous system vasculitis (primary CNS vasculitis) is a rare inflammatory disorder that affects small-to-medium-sized cerebral vessels, often leading to recurrent strokes. Diagnosis is vague due to non-specific neurological symptoms. Imaging findings, cerebrospinal fluid (CSF) analysis and exclusion of systemic vasculitis are essential for diagnosis.
View Article and Find Full Text PDFAcute Pancreatitis Associated with Tacrolimus in A Lung Transplant Recipient: A Case Report and Review of Literature.
Eur J Case Rep Intern Med
July 2025
Intensive care unit, Clinical Hospital Sveti Duh, Zagreb, Croatia.
Background: Tacrolimus is a commonly used immunosuppressant with well-defined side effects, including hypertriglyceridemia and hyperglycaemia. However, acute pancreatitis is still not widely recognized as an adverse event related to tacrolimus.
Case Presentation: A 60-year-old male was admitted to the intensive care unit with symptoms and signs of acute pancreatitis.
Immunoglobulin A Nephropathy: Molecular Pathogenesis and Targeted Therapy.
MedComm (2020)
September 2025
Immunoglobulin A nephropathy (IgAN), the most prevalent primary glomerulonephritis globally, is characterized by mesangial IgA deposition and heterogeneous clinical trajectories. Historically, management relied on renin-angiotensin system inhibition and empirical immunosuppression, yet high lifetime kidney failure risk persists despite optimized care. This review synthesizes advances in molecular pathogenesis, highlighting how the traditional multi-hit hypothesis-while foundational for targeted therapy development-fails to capture IgAN's recurrent, self-amplifying nature.
View Article and Find Full Text PDF