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The arterial switch operation with the Lecompte maneuver has become the therapy of choice for dextro-transposition of the great arteries, contributing to the improved survival rate of patients. Nevertheless, there have been few case reports addressing anesthetic management using one-lung ventilation in patients with an arterial switch. A 24-year-old man who underwent an arterial switch operation at 10 days of age was admitted for a right spontaneous pneumothorax. Preoperative transthoracic echocardiography revealed significant neo-aortic regurgitation, tricuspid regurgitation, and estimated right ventricular systolic pressure at the upper normal limit, all of which can be observed after the procedure. The pulmonic valve and pulmonary artery were difficult to delineate by transthoracic echocardiography. Instead, a plain CT demonstrated non-stenotic pulmonary arteries. During left isolated ventilation in the lateral decubitus position, the patient's hemodynamics and oxygenation were both well maintained, and a right thoracoscopic bullectomy was performed uneventfully under total intravenous anesthesia with propofol and remifentanil. Vital signs were also stable postoperatively, and the patient was discharged on the fifth postoperative day without adverse cardiovascular events. In the present case, the non-stenotic left pulmonary artery was considered to have played a vital role in successful one-lung ventilation, highlighting the importance of multimodal evaluation for long-term cardiac complications in a patient who underwent an arterial switch operation.
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http://dx.doi.org/10.7759/cureus.88547 | DOI Listing |
Thromb Res
September 2025
Departamento de Química and Institute for advanced research in chemical Science (IAdChem), Facultad de Ciencias, Módulo 13, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
Platelet integrin αIIbβ3 is the final common effector of arterial thrombosis: it switches from a low-affinity to a high-affinity state, binds fibrinogen, and initiates the outside-in signals that stabilize a growing clot. Calcium- and integrin-binding protein 1 (CIB1) emerged as the first endogenous partner of the αIIb cytoplasmic tail and is now recognized as a dual-role adaptor. At rest, Ca-free CIB1 tethers the inner membrane clasp and restrains premature integrin activation; after ligand engagement, Ca-bound CIB1 docks onto αIIb, recruits focal-adhesion kinase and amplifies Src-dependent cytoskeletal remodeling.
View Article and Find Full Text PDFWorld J Pediatr Congenit Heart Surg
September 2025
Department of Cardiology, Boston Children's Hospital, Boston, MA, USA.
There is a paucity of data available regarding operative timing and approach for d-loop transposition of the great arteries (dTGA) with intact ventricular septum (IVS) in premature infants. We reviewed our surgical experience in a case series of five premature infants (<37 weeks gestational age) with dTGA/IVS and birthweights <2.0 kg.
View Article and Find Full Text PDFCureus
August 2025
Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, JPN.
Cerebral infarction is a rare but serious complication after pulmonary resection for lung cancer. A 78-year-old man with hypertension and diabetes underwent video-assisted thoracoscopic right middle lobectomy for stage IA2 adenocarcinoma. On postoperative day 1, he developed acute right hemiparesis and motor aphasia.
View Article and Find Full Text PDFSci Prog
September 2025
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Single coronary ostium and intramural coronary artery variations in patients with transposition of the great arteries significantly increase the mortality and morbidity after arterial switch operation (ASO). In these patients, the classic coronary button implantation may cause kinking or twisting of the coronary artery which can cause coronary insufficiency. This case series presents two patients, a 15-month-old girl with transposition of the great arteries and a 10-month-old boy with a Taussig-Bing anomaly.
View Article and Find Full Text PDFNeurol Med Chir (Tokyo)
September 2025
Department of Neurosurgery, Osaka University Graduate School of Medicine.
We aimed to report our experience with exoscopic keyhole clipping of unruptured middle cerebral artery aneurysms using multiple 4K 3-dimensional monitors.We performed sphenoid ridge keyhole clipping of unruptured middle cerebral artery aneurysms using the ORBEYE exoscope (Sony Olympus Medical Solutions, Inc., Tokyo, Japan) with multiple 4K 3-dimensional monitors in 19 patients in our institution from 2020 to 2023.
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