Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Chronic mucocutaneous candidiasis can be caused by an Inborn Error of Immunity, especially those affecting TH-17 / IL-17 responses. Through in-depth immunophenotyping and functional assays, we reveal the association between homozygous carriage of the common p.R381Q IL-23R genetic variant and increased candidiasis susceptibility, relying on disrupted IL-23-mediated IL-17 immunity.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277866 | PMC |
| http://dx.doi.org/10.1002/eji.70002 | DOI Listing |
Publication Analysis
Top Keywords
chronic mucocutaneous
8
mucocutaneous candidiasis
8
homozygosity common
4
common il23r
4
il23r r381q
4
r381q variant
4
variant associates
4
associates increased
4
increased susceptibility
4
susceptibility chronic
4