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Background: Body mass index (BMI) cut-off values have been proposed to determine eligibility for elective total hip arthroplasty (THA) in obese patients. However, the relationship between the severity of obesity and reoperations remains poorly understood. We evaluated whether the World Health Organization (WHO) obesity class is independently associated with the risk, invasiveness, or timing of reoperations after THA in obese patients.
Methods: There were 7,022 patients who had a BMI ≥ 30 who underwent elective, unilateral THA for primary osteoarthritis between 2016 and 2022 at a tertiary care institution. The patients were grouped according to the WHO obesity classification: class 1 (60.7%, n = 4,265); 2 (26.2%, n = 1,840); and 3 (13.1%, n = 917). A chart review was conducted to identify individuals who underwent any closed or open reoperation requiring anesthesia, and to determine characteristics, including invasiveness and timing. Kaplan-Meier survival analysis was used to estimate the probability of survival over time. The reoperation was defined as the event of interest. The Cox proportional hazards regression model was used to analyze the impact of obesity class on time to reoperation, adjusting for age, sex, race, and Charlson Comorbidity Index.
Results: There were 67 patients (1.0%) who required at least one reoperation, with 17 undergoing two or more. The reoperation rates for class 1, 2, and 3 were 1% (n = 44), 0.9% (n = 17), and 0.7% (n = 6), respectively (P = 0.77). There were five minor procedures (7.5%), 27 open procedures with or without liner exchange (40.3%), and 35 revisions with acetabular and/or femoral component exchange (52.2%) performed. Survival analysis did not show a statistically significant difference between groups.
Conclusions: In this cohort of obese patients who underwent THA, the WHO obesity class was not associated with risk, invasiveness, or timing of reoperations. Policies that preclude patients fromreceiving THA based solely on BMI may have limited efficacy in reducing reoperations following THA.
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http://dx.doi.org/10.1016/j.arth.2025.07.026 | DOI Listing |
Neurosurg Rev
September 2025
Service de Neurochirurgie, GHU-Paris Psychiatrie et Neurosciences, Site Sainte Anne, Paris, F-75014, France.
Awake craniotomy is the gold standard to achieve maximal safe resection of brain lesions located within eloquent areas. There are no established guidelines to assess patient's eligibility for awake craniotomy by weight class. This study assesses feasibility, safety, and efficacy of awake surgery by weight classes through an observational, retrospective, single-institution cohort analysis (2010-2024) of 526 awake craniotomies.
View Article and Find Full Text PDFEur J Heart Fail
September 2025
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX, USA.
Aims: Obesity is commonly hypothesized to lead to the development of heart failure (HF) in part due to increases in blood volume (BV) and left ventricular (LV) remodelling. Whether adiposity and obesity severity are associated with BV expansion and subsequent LV remodelling in middle-aged individuals at increased risk (IR) prior to the onset of HF is unknown.
Methods And Results: We analysed data from 96 middle-aged (40-64 years) non-obese (25.
Gastroenterol Hepatol
September 2025
Balearic Health Service, Mallorca, Spain; ADEMA-Health Group of IUNICS, Balearic Islands, Spain. Electronic address:
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health concern, particularly among individuals with obesity. While metabolic and behavioral risk factors have been well described, the role of psychosocial determinants, such as weight stigma, remains underexplored.
Objectives: To assess the association between sociodemographic variables, healthy lifestyle behaviors, and internalized weight stigma with MASLD risk in a large cohort of obese workers across Spain.
Rheumatol Int
September 2025
Department of Physical Medicine and Rehabilitaton, Ankara Bilkent City Hospital, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Türkiye, Turkey.
The Impact of Obesity and Overweight on Rheumatoid Arthritis Patients: Real-World Insights from a Biologic and Targeted Synthetic DMARDs Registry. The management of rheumatoid arthritis (RA) has advanced with biological and targeted synthetic disease-modifying anti-rheumatic drugs (b/tsDMARDs). However, obesity, a common comorbidity, impacts treatment and disease progression efficacy.
View Article and Find Full Text PDFJ Metab Bariatr Surg
August 2025
Office of Medical Education, Seoul National University College of Medicine, Seoul, Korea.
Obesity represents a major global health challenge, requiring interventions that are both effective and economically sustainable. This review examines the cost-effectiveness of commonly discussed treatment options: glucagon-like peptide-1 receptor agonists (GLP-1 RAs), endoscopic sleeve gastroplasty (ESG), and metabolic/bariatric surgery (MBS). We synthesized evidence from published clinical studies and economic analyses, comparing incremental cost-effectiveness ratios (ICERs) and cost per quality-adjusted life year across obesity severity classes, with particular consideration of implications for Korea's healthcare context.
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