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Objective: To determine the intrarater and interrater reliability of the Five Step Assessment (FSA) and its derived coefficients of impairment in chronic spastic paresis.
Design: Prospective observational study.
Setting: Study of outpatients followed in a rehabilitation department.
Participants: In this single-center prospective study, participants (n=18) with chronic hemiparesis (>1y since injury) were evaluated by 4 raters (3 medical doctors, 1 physiotherapist; experience in hemiparesis, 14±9y).
Interventions: All raters estimated muscle shortening, spasticity, weakness, and fatigability against the resistance of 8 key antagonists in adults twice, one week apart.
Main Outcome Measures: FSA involves measuring 4 angles: angle of arrest at slow speed of stretch (X), angle of catch or clonus at fast speed of stretch (X, Tardieu), angle of match between maximal agonist effort and passive and active antagonist resistances (X), residual angle of match after 15 seconds of repeated maximal amplitude active efforts (X), and spasticity grade Y. Four derived coefficients of impairment were studied: coefficients of shortening, C(X-X)/X (X, normally expected maximal passive joint amplitude); of spasticity, C=(X-X)/X; of weakness, C=(X-X)/X; and of fatigability, C=(X-X)/X. Both intraclass correlation coefficients and mean differences were calculated for each parameter.
Results: Among 18 participants (four women), intrarater reliability was good to excellent (intraclass correlation coefficient >0.75) for all parameters in all muscles. Interrater reliability was good to excellent for all muscles and parameters except for spasticity grade Y and coefficient of fatigability (moderate).
Conclusions: The 5 parameters and 4 coefficients of impairment of the FSA have moderate-to-excellent intrarater and interrater reliability in chronic spastic paresis.
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http://dx.doi.org/10.1016/j.arrct.2025.100444 | DOI Listing |
Int J Rehabil Res
September 2025
Visual Impairments, Faculty of Education and Rehabilitation Sciences, University of Zagreb, Zagreb, Croatia.
The Visual Function Classification System (VFCS) provides a standardised framework for grading visual functioning in children with cerebral palsy (CP). This study evaluated the reliability and construct validity of the Croatian VFCS, and its ability to distinguish visual functioning across CP subtypes and functional classifications. Ninety-five children with CP (mean age: 11.
View Article and Find Full Text PDFEur J Neurol
September 2025
Department of Neurology and Center for Translational and Behavioral Neurosciences, University Medicine Essen, University of Duisburg-Essen, Essen, Germany.
Background: Changes in handgrip strength have recently been adapted as clinical biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) under the assumption of a disease-specific peripheral neuromuscular dysfunction. However, some have proposed that strength impairments in ME/CFS are better explained by alterations in higher-order motor control. In serial measurements, exertion can been assessed through analysis of variation, since maximal voluntary contractions exhibit lower coefficients of variation (CV) than submaximal contractions.
View Article and Find Full Text PDFAnn Vasc Surg
September 2025
Vascular Medicine Department, University Hospital, Angers, FRANCE; UMR CNRS 1083 INSERM 6015, LUNAM University, Angers, FRANCE. Electronic address:
Introduction: Thoracic Outlet Syndrome (TOS) is characterized by the positional compression of the brachial plexus and/or subclavian vessels in the cervico-thoraco-brachial region, unilaterally or bilaterally. The functional impact is currently assessed by questionnaires that do not allow side-specific assessment. The Mobility of Arm Score (MASC) questionnaire was designed to be short and assess the functional impact of suspected TOS, emphasizing dynamic tasks and side-specific evaluations.
View Article and Find Full Text PDFTransl Anim Sci
May 2025
Carthage Veterinary Service Ltd., Carthage, IL 62321, USA.
Soybean meal (SBM) contains many bioactive compounds, such as isoflavones, which possess anti-inflammatory and anti-oxidative properties that may provide nutritional intervention to pigs infected with porcine reproductive and respiratory syndrome virus (PRRSv). The disease results in abortions, stillborn piglets, and overall impairs reproductive success in sows. Today, there are no data available on feeding SBM to sows infected with PRRSv to mitigate the negative impacts of PRRSv on sow and litter performance.
View Article and Find Full Text PDFInt Ophthalmol
September 2025
Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology and Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technolog
Purpose: To analyze macular microvascular networks and investigate correlations between visual acuity and quantitative parameters in patients with Leber's hereditary optic neuropathy (LHON) using optical coherence tomography angiography (OCTA).
Methods: An observational, cross-sectional study was conducted, including 25 eyes from 25 genetically confirmed chronic LHON patients and 25 eyes from 25 age-matched healthy controls. Images were obtained using a spectral domain OCTA system.