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Background: Himalayan forests are fragile, rich in biodiversity, and face increasing threats from anthropogenic pressures and climate change. Assessing their health is critical for sustainable forest management. This study integrated ecological indicators (tree density, size, regeneration, deforestation, slope, grazing, and erosion) with machine learning (ML) to classify forest health and identify key drivers across 37 Western Himalayan sites. Principal component analysis (PCA) reduced data dimensionality, highlighting major ecological gradients. K-means clustering was used to group forests into three distinct classes based on ecological characteristics, due to its efficiency in identifying natural patterns within multivariate data. ML models, including Decision Tree (DT), Random Forest (RF), and Support Vector Machine (SVM) were trained and validated using an 80:20 train-test split and 5-fold cross-validation.
Results: PCA revealed that elevation, disturbance, and regeneration explained 74.3% variance. Forest health varied across sites, with 10 categorized as healthy, 19 as moderate, and 8 as unhealthy. Forest regeneration was highly skewed (2.67) and leptokurtic (9.8), with few sites showing high seedling abundance, while deforestation (mean = 294 stumps ha) indicated uneven human impact. Among ML models, RF showed the best performance with a mean accuracy of 0.83, Kappa 0.87, and balanced accuracy 0.88. SVM followed with 0.75 accuracy, Kappa 0.70, and balanced accuracy 0.81. DT performed lowest with 0.66 accuracy and Kappa 0.45. Cross-validation confirmed RF's highest mean accuracy (90.3%), followed by SVM (88.1%) and DT (65.1%). RF-based feature importance analysis showed tree DBH, height, regeneration rate, soil erosion, and tree density as key ecological drivers of forest health.
Conclusions: This study highlights ML-driven classification as a precise, scalable, and objective tool for large-scale forest health assessments. Conservation efforts should prioritize degraded forests through afforestation, slope stabilization, controlled grazing, erosion management, and continuous ecosystem monitoring. Future studies should integrate high-resolution remote sensing (e.g., Landsat, Sentinel-2) and climate datasets (e.g., temperature, precipitation, and drought indices) to enhance predictive capabilities and support long-term forest management planning. The findings underscore the value of data-driven approaches, establishing machine learning as an effective tool to enhance forest monitoring and support evidence-based forest conservation and management in the Himalayas.
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http://dx.doi.org/10.1186/s12870-025-06937-5 | DOI Listing |
Obesity (Silver Spring)
September 2025
Division of Hematology, Oncology, and Palliative Care, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Objective: From October 18-20, 2022, the National Institutes of Health held a workshop to examine the state of the science concerning obesity interventions in adults to promote health equity. The workshop had three objectives: (1) Convene experts from key institutions and the community to identify gaps in knowledge and opportunities to address obesity, (2) generate recommendations for obesity prevention and treatment to achieve health equity, and (3) identify challenges and needs to address obesity prevalence and disparities, and develop a diverse workforce.
Methods: A three-day virtual convening.
Glob Chang Biol
September 2025
European Centre for Medium-Range Weather Forecast (ECMWF), Reading, UK.
The catastrophic Los Angeles Fires of January 2025 underscore the urgent need to understand the complex interplay between hydroclimatic variability and wildfire behavior. This study investigates how sequential wet and dry periods, hydroclimatic rebound events, create compounding environmental conditions that culminate in extreme fire events. Our results show that a cascade of moisture anomalies, from the atmosphere to vegetation health, precedes these fires by around 6-27 months.
View Article and Find Full Text PDFFront Immunol
September 2025
Guangxi Key Laboratory of AIDS Prevention and Treatment & School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Background: People living with HIV(PLWH) are a high-risk population for cancer. We conducted a pioneering study on the gut microbiota of PLWH with various types of cancer, revealing key microbiota.
Methods: We collected stool samples from 54 PLWH who have cancer (PLWH-C), including Kaposi's sarcoma (KS, n=7), lymphoma (L, n=22), lung cancer (LC, n=12), and colorectal cancer (CRC, n=13), 55 PLWH who do not have cancer (PLWH-NC), and 49 people living without HIV (Ctrl).
Front Oncol
August 2025
Department of Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Introduction: Metastatic colorectal cancer (mCRC) exhibits significant heterogeneity in molecular profiles, influencing treatment response and patient outcomes. Mutations in v-raf murine sarcoma viral oncogene homolog B1 () and rat sarcoma () family genes are commonly observed in mCRC. Though originally thought to be mutually exclusive, recent data have shown that patients may present with concomitant and mutations, posing unique challenges and implications for clinical management.
View Article and Find Full Text PDFFront Public Health
September 2025
Department of Personnel Strategies, Institute of Management, Collegium of Management and Finance, SGH Warsaw School of Economics, Warsaw, Poland.
Introduction: Organizational resilience is of paramount importance for coping with adversity, particularly in the healthcare sector during crises. The objective of the present study was to evaluate the impact of resilience-based interventions on the well-being of healthcare employees during the pandemic. In this study, resilience-based interventions are defined as organizational actions that strengthen a healthcare institution's capacity to cope with crises-such as ensuring adequate personal protective equipment and staff testing, clear risk-communication, alternative care pathways (e.
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