98%
921
2 minutes
20
We elucidated the stimuli-responsive phase transition in a synthetic model of marginally stable proteins composed of poly(-isopropylacrylamide) with incorporated redox-responsive sites. Redox-state changes in a single redox-responsive site were efficiently converted to hydration and dehydration of multiple monomer units within the polymer chain synchronized with electron transfer.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1039/d5cc02924d | DOI Listing |
Khirurgiia (Mosk)
September 2025
Mogilev Regional Clinical Hospital, Mogilev, Republic of Belarus.
Objective: To evaluate clinical and laboratory effectiveness of ultrasound treatment for purulent wounds.
Material And Methods: The study enrolled 46 patients with purulent wounds divided into the main group (23 patients, ultrasonic treatment) and the control group (23 patients, traditional treatment). We assessed treatment effectiveness considering visual data, quality of granulation tissue, wound defect area and marginal epithelialization, complete blood count and C-reactive protein.
Climacteric
September 2025
Gynecology Discipline, Obstetrics and Gynecology Department, University of São Paulo School of Medicine, São Paulo, Brazil.
Objective: Social media is an increasingly relevant tool for health education, enabling information exchange, promoting autonomy and supporting informed decision-making. This study introduces Menopausando, a predominantly Portuguese-language digital platform designed to support women during menopausal transition and postmenopause.
Method: This cross-sectional study has been carried out in the Gynecology Discipline, São Paulo University, Brazil, since 2019.
Epilepsia
September 2025
Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA.
The rate of sudden unexpected death in epilepsy (SUDEP) is ~1 per 1000 patients each year. Terminal events reportedly involve repeated and prolonged apnea, suggesting a failure to autoresuscitate. To better understand the mechanisms and identify novel therapeutics, standardized tests to screen for autoresuscitation efficacy are needed in preclinical SUDEP.
View Article and Find Full Text PDFJ Phys Chem B
September 2025
Chemistry Division, Code 6176, US Naval Research Laboratory, Washington, D.C. 20375, United States.
Amyloid materials are formed from the aggregation of single proteins, yet contain polymorphisms where bulk properties are defined by a composition of multiple fibril types. Though desirable as a sustainable material, little is known about how various fibril types survive at high temperatures or in nonpolar solvents due to their highly similar molecular and nanoscale features. Here, we demonstrate that in situ two-dimensional infrared spectroscopy (2DIR), when paired with nanoscale microscopy, can determine the transition temperature of amyloid subpopulations without the use of labels.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) State Key Laboratory of Advanced Chemical Power Sources, College of Chemistry, Nankai University, Tianjin 300071, China.
Developing cost-effective spinel oxide catalysts with both high oxygen evolution reaction (OER) activity and stability is crucial for advancing sustainable clean energy conversion. However, practical applications are often hindered by the activity limitations inherent in the adsorbate evolution mechanism (AEM) and the stability limitations associated with the lattice oxygen mechanism (LOM). Herein, we demonstrate structural changes induced by phase transformation in CoMn spinel oxides, which yield more active octahedral sites with shortened intersite distance.
View Article and Find Full Text PDF