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Article Abstract
A new 3,4-secodammarane derivative () was obtained from the bark of . The combination of spectral analysis and the computation of electronic circular dichroism (ECD) has definitively confirmed the absolute configuration of the compound. This configuration has been identified as methyl (20S, 24 R)-epoxy-25-hydroxy-3,4-secodammar-4(28)-en-29-al-3-oate. Furthermore, Compound exhibited notable inhibitory effects on two specific cancer cell lines: the MDA-MB-231 and the SW620. The calculated IC values for these cell lines were found to be 23.02 and 20.88 μM, respectively, indicating a significant potential for this compound in therapeutic applications against these types of cancer.
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| http://dx.doi.org/10.1080/14786419.2025.2532842 | DOI Listing |
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