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Abstract: Using the travel time of sound waves advected by a moving carrier medium, acoustic tomography allows to reconstruct temperature and flow fields in opaque fluids without tracers or scattering particles. Reconstruction algorithms are conventionally based on the ray approximation and pose difficulties, especially in enclosed domains: Interferences of early reflections can prevent the assignment of each arrival to the correct ray path. We develop a full-waveform inversion for acoustic tomography in laboratory-scale experiments, perform synthetic tests, and benchmark these with a straight-ray algorithm. Multiple late arrivals of reflected waves are considered in order to increase the quality of the reconstructions when restricted to a sparse transducer array. In addition, the full-waveform algorithm allows to invert simultaneously emitted signals from all sources, decreasing the acquisition time in which a flow must be assumed stationary. These findings make the new method especially interesting for researchers experimenting with enclosed, opaque fluids where no optical imaging is feasible. Furthermore, we envision a potential application of the newly developed method to map flows around objects or complex wall geometries and even multiphase flows.
Supplementary Information: The online version contains supplementary material available at 10.1007/s00348-025-04068-z.
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http://dx.doi.org/10.1007/s00348-025-04068-z | DOI Listing |
Ann Anat
September 2025
Division of Anatomy, Department 1, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, Bucharest 050474, Romania. Electronic address:
Purpose: This study aimed to investigate the prevalence and anatomical patterns of temporal bone pneumatisation surrounding the internal acoustic meatus (IAM), specifically across its three anatomical regions: the porus acusticus internus (medial opening), the proper IAM (tubular midportion), and the fundus (lateral end). A secondary objective was to evaluate the association between pneumatisation and the thickness of the overlying tegmen in each region.
Methods: A total of 160 IAMs (80 patients, bilateral assessment) were analyzed using cone-beam computed tomography (CBCT).
IEEE Trans Biomed Eng
September 2025
Diagnostic ultrasound has long filled a crucial niche in medical imaging thanks to its portability, affordability, and favorable safety profile. Now, multi-view hardware and deep-learning-based image reconstruction algorithms promise to extend this niche to increasingly sophisticated applications, such as volume rendering and long-term organ monitoring. However, progress on these fronts is impeded by the complexities of ultrasound electronics and by the scarcity of high-fidelity radiofrequency data.
View Article and Find Full Text PDFJ Control Release
September 2025
Research Department of Imaging Chemistry and Biology, School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom. Electronic address:
The blood-brain barrier (BBB) significantly hinders the treatment of central nervous system (CNS) disorders and brain tumors with intact BBB by restricting the entry of most therapeutic agents, including small-molecule drugs and particularly larger macromolecules. Liposomal formulations, such as PEGylated liposomes with long blood half-lives, high drug-carrying capacity, and reduced off-site toxicity, can be useful for brain drug delivery, but their large size often limits BBB penetration. A novel liposomal doxorubicin formulation(Talidox®) with a smaller size (~36 nm, determined by TEM), increased blood circulation half-life (median reported half-life 96 h), and better stability than previous clinical formulations, can be a suitable choice for brain delivery.
View Article and Find Full Text PDFRespir Med Case Rep
August 2025
Division of Respiratory Medicine, Saiseikai Kumamoto Hospital, Kumamoto, Japan.
A cholecystopleural fistula is an extremely rare condition characterized by abnormal communication between the gallbladder and pleural cavity. This abnormal connection can lead to the leakage of bile or infectious material into the pleural space, potentially causing infected biliothorax. Here, we report a case of recurrent infected biliothorax caused by a cholecystopleural fistula in a 77-year-old man.
View Article and Find Full Text PDFJ Acoust Soc Am
September 2025
Department of Intermedia Art and Science, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan.
Acousto-optic tomography (AOT), a technology that reconstructs two- or three-dimensional sound fields from optically measured sound-field projections, has been widely studied as an efficient and high-spatial-resolution method for sound field observations. Recently, physical-model-based approaches have made significant progress, with higher accuracy and fewer sampling requirements than conventional methods. Nevertheless, it remains a challenge to reconstruct three-dimensional outgoing sound waves in the volume surrounding a sound source due to constraints on existing methods both in mathematical formulation and measurement systems.
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