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Background: Hemiplegic shoulder pain (HSP) is a prevalent and disabling condition affecting patients after stroke or traumatic brain injury. There is currently no consensus regarding infiltrative strategies. A combined approach, involving suprascapular nerve block and intra-articular corticosteroid injection, has been proposed for HSP and capsulitis, yet evidence remains limited.
Objective: This study presents the results (efficacy and safety) of this combined approach to alleviate pain and improve passive range of motion (PROM).
Methods: A retrospective, multicenter observational study (36 patients).
Results: At 1 month, the mean pain intensity (visual analogue scale VAS) significantly decreased from 6.5 ± 1.5 at baseline to 1.9 ± 2.1, and PROM showed significant improvement across all three planes (mean PROM gains: 28.4° in abduction, 29.2° in flexion, and 13.4° in external rotation). The benefits were largely maintained at 3 months, and no serious complications were observed (one vasovagal episode).
Conclusion: The combined approach is a clinically feasible, safe, and effective method for treating HSP in PRM settings.
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http://dx.doi.org/10.3389/fneur.2025.1620168 | DOI Listing |
Lab Anim Res
September 2025
Korea Model Animal Priority Center (KMPC), Seoul, Republic of Korea.
Background: Laboratory animal veterinarians play a crucial role as a bridge between the ethical use of laboratory animals and the advancement of scientific and medical knowledge in biomedical research. They alleviate pain and reduce distress through veterinary care of laboratory animals. Additionally, they enhance animal welfare by creating environments that mimic natural habitats through environmental enrichment and social associations.
View Article and Find Full Text PDFNeurol Res Pract
September 2025
German Neurological Society, Berlin, Germany.
Background: Recreational nitrous oxide (NO) abuse has become increasingly prevalent, raising concerns about associated health risks. In Germany, the lack of reliable data on NO consumption patterns limits the development of effective public health interventions. This study aims to address this knowledge gap by examining trends, determinants, and health consequences of NO abuse in Germany.
View Article and Find Full Text PDFEur J Med Res
September 2025
Department of Zoology, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
Nuclear receptors (NRs) are a superfamily of ligand-activated transcription factors that regulate gene expression in response to metabolic, hormonal, and environmental signals. These receptors play a critical role in metabolic homeostasis, inflammation, immune function, and disease pathogenesis, positioning them as key therapeutic targets. This review explores the mechanistic roles of NRs such as PPARs, FXR, LXR, and thyroid hormone receptors (THRs) in regulating lipid and glucose metabolism, energy expenditure, cardiovascular health, and neurodegeneration.
View Article and Find Full Text PDFBMC Womens Health
September 2025
Society for Family Health-Nigeria, Abuja, Nigeria.
Background: Interventions aimed to increase healthcare provider empathy and capacity to deliver person-centered care have been shown to improve healthcare seeking and outcomes. In the context of self-injectable contraception, empathetic counseling and coaching may be promising approaches for addressing "fear of the needle" among clients interested in using subcutaneous depot medroxyprogesterone (DMPA-SC). In Nigeria, the Delivering Innovation in Self-Care (DISC) project developed and evaluated an empathy-based in-service training and supportive supervision intervention for public sector family (FP) planning providers implemented in conjunction with community-based mobilization.
View Article and Find Full Text PDFInt J Colorectal Dis
September 2025
Proctology Department, Diaconesses Croix Saint-Simon Hospital Group, 125 Rue d'Avron, 75020, Paris, France.
Background And Aims: This study aimed to describe Crohn's disease perianal fistulizing lesions in patients undergoing surgery over 60 years to compare clinical presentation, management and outcomes with those observed in younger patients.
Methods: Between January 2012 and December 2022, all patients over 60 years old who underwent a first surgical intervention for anal fistula at two medical centers were included. For each patient included, two younger patients who underwent the same surgical procedure during the same period in the same centers were matched for comparison.